Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 4860346..4860893 Replicon chromosome
Accession NZ_CP115669
Organism Pseudomonas sp. PSE14

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag O6P39_RS22265 Protein ID WP_275608583.1
Coordinates 4860606..4860893 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag O6P39_RS22260 Protein ID WP_275608582.1
Coordinates 4860346..4860615 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O6P39_RS22235 (O6P39_22235) 4855413..4856531 - 1119 WP_275608577.1 sensor domain-containing diguanylate cyclase -
O6P39_RS22240 (O6P39_22240) 4856792..4858315 + 1524 WP_275608578.1 fumarate hydratase -
O6P39_RS22245 (O6P39_22245) 4858555..4858857 - 303 WP_275608579.1 ribbon-helix-helix domain-containing protein -
O6P39_RS22250 (O6P39_22250) 4858891..4859472 - 582 WP_275608580.1 DJ-1/PfpI family protein -
O6P39_RS22255 (O6P39_22255) 4859579..4860157 - 579 WP_275608581.1 DUF2846 domain-containing protein -
O6P39_RS22260 (O6P39_22260) 4860346..4860615 + 270 WP_275608582.1 CopG family ribbon-helix-helix protein Antitoxin
O6P39_RS22265 (O6P39_22265) 4860606..4860893 + 288 WP_275608583.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O6P39_RS22270 (O6P39_22270) 4860887..4861777 - 891 WP_275608584.1 carbon-nitrogen hydrolase family protein -
O6P39_RS22275 (O6P39_22275) 4861777..4862370 - 594 WP_275608585.1 GNAT family acetyltransferase -
O6P39_RS22280 (O6P39_22280) 4862480..4862878 + 399 WP_275608586.1 nuclear transport factor 2 family protein -
O6P39_RS22285 (O6P39_22285) 4863180..4864460 - 1281 WP_275608587.1 acyltransferase -
O6P39_RS22290 (O6P39_22290) 4864505..4865662 - 1158 WP_275608588.1 phospholipase D-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-93)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-39)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10890.54 Da        Isoelectric Point: 9.9124

>T267247 WP_275608583.1 NZ_CP115669:4860606-4860893 [Pseudomonas sp. PSE14]
MRVIYAPAALRDLERLRRFLRETNPTAARRAGQIILQATQALGAHPQMGRLIDDLPVVYREWPIDFGDSGYLARYRIDGE
TLVVLAIRHQREAGY

Download         Length: 288 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10499.64 Da        Isoelectric Point: 4.4422

>AT267247 WP_275608582.1 NZ_CP115669:4860346-4860615 [Pseudomonas sp. PSE14]
MATSVKLDEEMLARVRELAELRQRSPHWIMREAIGQYVVREEQREKLKRDTEQAWEEFQATGQHVTAEAVENWLNSWGDE
DEQAAPKCE

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References