Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 1652754..1654241 Replicon chromosome
Accession NZ_CP115669
Organism Pseudomonas sp. PSE14

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag O6P39_RS07805 Protein ID WP_275610803.1
Coordinates 1652754..1653323 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag O6P39_RS07810 Protein ID WP_275610804.1
Coordinates 1653390..1654241 (+) Length 284 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O6P39_RS07795 (O6P39_07795) 1648421..1648879 + 459 WP_275610801.1 DMT family transporter -
O6P39_RS07800 (O6P39_07800) 1649004..1652480 - 3477 WP_275610802.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -
O6P39_RS07805 (O6P39_07805) 1652754..1653323 + 570 WP_275610803.1 GNAT family protein Toxin
O6P39_RS07810 (O6P39_07810) 1653390..1654241 + 852 WP_275610804.1 AraC family transcriptional regulator Antitoxin
O6P39_RS07815 (O6P39_07815) 1654383..1656548 + 2166 WP_275610805.1 TonB-dependent receptor family protein -
O6P39_RS07820 (O6P39_07820) 1656730..1658604 + 1875 WP_275610806.1 MFS transporter -
O6P39_RS07825 (O6P39_07825) 1658668..1658877 - 210 WP_024763416.1 cold-shock protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(197-274)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21172.44 Da        Isoelectric Point: 9.6199

>T267246 WP_275610803.1 NZ_CP115669:1652754-1653323 [Pseudomonas sp. PSE14]
MFRPLPITLQRGALRLEPMVEADVPELVSLAEANREVLQFMSAPGRPDWYRQGLADQREGRALPLVVRLGNEIVGTTRFM
DFLPALPACEIGATWLDQAQHGSGLNATMKYLMLRHAFDSWKMVRVQIKTAASNLRSQRAIEKLGAVREGVLRNHRRLAG
GRLDDTILYSITDHEWPQVKAALEAGFNG

Download         Length: 570 bp

Antitoxin


Download         Length: 284 a.a.        Molecular weight: 31480.87 Da        Isoelectric Point: 7.4035

>AT267246 WP_275610804.1 NZ_CP115669:1653390-1654241 [Pseudomonas sp. PSE14]
MTEHHASGERTRFWRAQELGGVELLHARYIEQVFAPHVHEGFAFVMIEQGAQRFHHRGSEHFAPTGSVVLINPDEVHTGS
KADEAGWLYRGFYPELEQVSGILDELELGRSGTPSFAASVLQDPELVQVLLGAHRLLESEATVLQRQTCWREALLLLFQR
HARIPEVPAAGNEPLAVARARELLGARLIDPPSLEELAAAVALSPFHFARVFRKATGLPPHAWLKQRRLEQARALLKQGC
APVNVAMHLGFADQSHLSRQFKQAYGVGPGEYRQACARSFKTA

Download         Length: 852 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References