Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 1637686..1638825 Replicon chromosome
Accession NZ_CP115669
Organism Pseudomonas sp. PSE14

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag O6P39_RS07755 Protein ID WP_275610795.1
Coordinates 1638055..1638825 (+) Length 257 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag O6P39_RS07750 Protein ID WP_275610794.1
Coordinates 1637686..1638054 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O6P39_RS07715 (O6P39_07715) 1633220..1634413 + 1194 WP_275610790.1 outer membrane protein assembly factor BamC -
O6P39_RS07720 (O6P39_07720) 1634352..1635110 + 759 WP_275610791.1 MBL fold metallo-hydrolase -
O6P39_RS07725 (O6P39_07725) 1635141..1635851 + 711 WP_038803299.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
O6P39_RS07735 (O6P39_07735) 1636123..1636497 - 375 WP_275610792.1 hypothetical protein -
O6P39_RS07740 (O6P39_07740) 1636599..1636943 - 345 WP_207885013.1 carboxymuconolactone decarboxylase family protein -
O6P39_RS07745 (O6P39_07745) 1637060..1637542 - 483 WP_275610793.1 transcription elongation factor GreAB -
O6P39_RS07750 (O6P39_07750) 1637686..1638054 + 369 WP_275610794.1 DUF2384 domain-containing protein Antitoxin
O6P39_RS07755 (O6P39_07755) 1638055..1638825 + 771 WP_275610795.1 RES family NAD+ phosphorylase Toxin
O6P39_RS07760 (O6P39_07760) 1639702..1641066 + 1365 WP_275611909.1 DNA recombination protein RmuC -
O6P39_RS07765 (O6P39_07765) 1641340..1642686 - 1347 WP_275610796.1 FAD-binding oxidoreductase -
O6P39_RS07770 (O6P39_07770) 1642772..1643662 - 891 WP_275610797.1 metal-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(68-212)

Antitoxin

Cro/C1-type helix-turn-helix domain

(22-50)


Sequences

Toxin        


Download         Length: 257 a.a.        Molecular weight: 28993.15 Da        Isoelectric Point: 8.4574

>T267245 WP_275610795.1 NZ_CP115669:1638055-1638825 [Pseudomonas sp. PSE14]
MSFETGAQIWARHAPESVVSPIRGRLVRLVESQGQVATLQLVDTLAEQALLEELLETSKPHVPPPAEHLHYLLKTPFRYP
PLRWGSRFGRRHEPSLFYAALKLDTAMAESAFYRYVLWEGMSSPPPSGRILSEHASFEARFQVQRGVRLQLPPFREYEPA
LRDPSDYRVAQGLGSAMREAGVEAFEYRSARCPHAGVNVALFAPSAFTEKRPRNLMPWLCETTAEYVAFKHAQVPDTPRL
FPRAQFLVDGHLPYPA

Download         Length: 771 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13434.69 Da        Isoelectric Point: 9.7742

>AT267245 WP_275610794.1 NZ_CP115669:1637686-1638054 [Pseudomonas sp. PSE14]
MSALLRESPAADAVLAKAVLTAREHLAMTQQELAAIVGVERSAVSRWKQGGLRVDSKTGELALLLVRVYRALFALFGGNL
EDMRHFLRTENRHLNGVPLQLMEQVQGLVAVVEYLDAIRGKV

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References