Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 499191..499870 Replicon chromosome
Accession NZ_CP115668
Organism Cutibacterium sp. CBA3108

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O6R08_RS02255 Protein ID WP_271418558.1
Coordinates 499442..499870 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O6R08_RS02250 Protein ID WP_271418557.1
Coordinates 499191..499442 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O6R08_RS02245 (O6R08_02245) 498384..498947 + 564 WP_271418556.1 NADPH-dependent FMN reductase -
O6R08_RS02250 (O6R08_02250) 499191..499442 + 252 WP_271418557.1 hypothetical protein Antitoxin
O6R08_RS02255 (O6R08_02255) 499442..499870 + 429 WP_271418558.1 PIN domain-containing protein Toxin
O6R08_RS02260 (O6R08_02260) 500049..503639 + 3591 WP_271418559.1 helicase-related protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-134)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15335.64 Da        Isoelectric Point: 6.2100

>T267241 WP_271418558.1 NZ_CP115668:499442-499870 [Cutibacterium sp. CBA3108]
MLLVDANVLVYATNTSAQHHEAARAWLLEELNSGTEVVGMPWVSLLGFIRVCTHPRILENPLTAEQAMSVVNAWLSHPRV
VTPEPSARHGALLAGLLVKAGTAGNLTNDAHLAALALELNATMVTFDRDFGRFDVRFLVPGS

Download         Length: 429 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.41 Da        Isoelectric Point: 5.1007

>AT267241 WP_271418557.1 NZ_CP115668:499191-499442 [Cutibacterium sp. CBA3108]
MRTTLTLDPDVTELLEREMAERHVSFKRVVNDALRRGLGSTQNVDFTFPSFNLGAARVDLTHAARLAAELEDDALAEKLS
QGR

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References