Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /RES-TIGR02293 |
Location | 2699967..2700850 | Replicon | chromosome |
Accession | NZ_CP115663 | ||
Organism | Pseudomonas putida strain PD584_L3 |
Toxin (Protein)
Gene name | - | Uniprot ID | Q88K57 |
Locus tag | PED35_RS12240 | Protein ID | WP_003250527.1 |
Coordinates | 2700413..2700850 (+) | Length | 146 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | I7C3Q7 |
Locus tag | PED35_RS12235 | Protein ID | WP_003250525.1 |
Coordinates | 2699967..2700416 (+) | Length | 150 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PED35_RS12210 (PED35_12210) | 2695391..2696590 | + | 1200 | WP_049587621.1 | sugar transporter | - |
PED35_RS12215 (PED35_12215) | 2696630..2697214 | - | 585 | WP_010953382.1 | LysE family transporter | - |
PED35_RS12220 (PED35_12220) | 2697265..2698095 | - | 831 | WP_003250518.1 | AraC family transcriptional regulator | - |
PED35_RS12225 (PED35_12225) | 2698144..2699067 | - | 924 | WP_010953383.1 | LysR family transcriptional regulator | - |
PED35_RS12230 (PED35_12230) | 2699171..2699824 | + | 654 | WP_010953384.1 | oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB | - |
PED35_RS12235 (PED35_12235) | 2699967..2700416 | + | 450 | WP_003250525.1 | DUF2384 domain-containing protein | Antitoxin |
PED35_RS12240 (PED35_12240) | 2700413..2700850 | + | 438 | WP_003250527.1 | RES family NAD+ phosphorylase | Toxin |
PED35_RS12245 (PED35_12245) | 2700858..2702012 | - | 1155 | WP_049587669.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
PED35_RS12250 (PED35_12250) | 2702206..2703132 | - | 927 | WP_010953387.1 | LysR family transcriptional regulator | - |
PED35_RS12255 (PED35_12255) | 2703273..2704502 | + | 1230 | WP_049587623.1 | acyl-CoA dehydrogenase | - |
PED35_RS12260 (PED35_12260) | 2704666..2704914 | + | 249 | Protein_2374 | PAAR domain-containing protein | - |
PED35_RS12265 (PED35_12265) | 2704917..2705306 | + | 390 | WP_049587628.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 146 a.a. Molecular weight: 15990.29 Da Isoelectric Point: 5.6007
>T267230 WP_003250527.1 NZ_CP115663:2700413-2700850 [Pseudomonas putida]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSAQPELTRTLGNRFLDDCSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSAQPELTRTLGNRFLDDCSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF
Download Length: 438 bp
Antitoxin
Download Length: 150 a.a. Molecular weight: 16956.46 Da Isoelectric Point: 5.7258
>AT267230 WP_003250525.1 NZ_CP115663:2699967-2700416 [Pseudomonas putida]
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL
Download Length: 450 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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