Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 4427313..4427877 Replicon chromosome
Accession NZ_CP115659
Organism Kosakonia oryzendophytica strain FY-07

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag O9K67_RS21330 Protein ID WP_245191397.1
Coordinates 4427313..4427621 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1C4A1Z8
Locus tag O9K67_RS21335 Protein ID WP_061497949.1
Coordinates 4427605..4427877 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O9K67_RS21305 (O9K67_21305) 4423404..4423871 - 468 WP_061497942.1 YjiG family protein -
O9K67_RS21310 (O9K67_21310) 4423864..4424547 - 684 WP_061497944.1 nucleoside recognition domain-containing protein -
O9K67_RS21315 (O9K67_21315) 4424925..4425821 + 897 WP_061497946.1 LysR substrate-binding domain-containing protein -
O9K67_RS21320 (O9K67_21320) 4425864..4426634 + 771 WP_061497947.1 AraC family transcriptional regulator -
O9K67_RS21325 (O9K67_21325) 4426684..4427307 + 624 WP_061497948.1 LysE family translocator -
O9K67_RS21330 (O9K67_21330) 4427313..4427621 - 309 WP_245191397.1 type II toxin-antitoxin system YafQ family toxin Toxin
O9K67_RS21335 (O9K67_21335) 4427605..4427877 - 273 WP_061497949.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
O9K67_RS21340 (O9K67_21340) 4427963..4429243 + 1281 WP_061497950.1 DUF445 domain-containing protein -
O9K67_RS21345 (O9K67_21345) 4429264..4429503 + 240 WP_061497952.1 DUF2164 domain-containing protein -
O9K67_RS21350 (O9K67_21350) 4429623..4430774 + 1152 WP_061497954.1 double-cubane-cluster-containing anaerobic reductase -
O9K67_RS21355 (O9K67_21355) 4430784..4431554 + 771 WP_061497956.1 putative 2-hydroxyacyl-CoA dehydratase activator YjiL -
O9K67_RS21360 (O9K67_21360) 4431547..4431783 + 237 WP_061497959.1 DUF3343 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(12-102)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-66)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11577.32 Da        Isoelectric Point: 9.3067

>T267219 WP_245191397.1 NZ_CP115659:c4427621-4427313 [Kosakonia oryzendophytica]
MMGKSKRAPLPYRSDYTKTFVKAWARYNKAGRRDMHETAAIMSMVLSGNPLPAQYSDHALTGNMLGFRELHLGGDYLLVY
RVDEAKHLVVFTDLGTHAELFE

Download         Length: 309 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10072.40 Da        Isoelectric Point: 6.4632

>AT267219 WP_061497949.1 NZ_CP115659:c4427877-4427605 [Kosakonia oryzendophytica]
MDSVIRSRIDSELKARAGLVLESCGLNWSTAIRLFAEQIVKSEGIPFEVTRKPTARLRNAMSEANEITTHQHGRFNGVEQ
LMDSLNDGKE

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1C4A1Z8

References