Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3346943..3347859 Replicon chromosome
Accession NZ_CP115659
Organism Kosakonia oryzendophytica strain FY-07

Toxin (Protein)


Gene name - Uniprot ID A0A1C4B0H3
Locus tag O9K67_RS16240 Protein ID WP_061494660.1
Coordinates 3347383..3347859 (+) Length 159 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag O9K67_RS16235 Protein ID WP_061494661.1
Coordinates 3346943..3347386 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O9K67_RS16210 (O9K67_16210) 3341980..3343746 + 1767 WP_061494664.1 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD -
O9K67_RS16215 (O9K67_16215) 3343747..3345468 + 1722 WP_061494663.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -
O9K67_RS16220 (O9K67_16220) 3345576..3346277 + 702 WP_061494662.1 leucyl/phenylalanyl-tRNA--protein transferase -
O9K67_RS16225 (O9K67_16225) 3346469..3346638 + 170 Protein_3192 hypothetical protein -
O9K67_RS16230 (O9K67_16230) 3346566..3346784 + 219 WP_001040187.1 translation initiation factor IF-1 -
O9K67_RS16235 (O9K67_16235) 3346943..3347386 + 444 WP_061494661.1 DUF2384 domain-containing protein Antitoxin
O9K67_RS16240 (O9K67_16240) 3347383..3347859 + 477 WP_061494660.1 RES domain-containing protein Toxin
O9K67_RS16245 (O9K67_16245) 3347976..3349364 + 1389 WP_061499941.1 diguanylate cyclase -
O9K67_RS16250 (O9K67_16250) 3349454..3351742 - 2289 WP_061494659.1 ATP-dependent Clp protease ATP-binding subunit ClpA -
O9K67_RS16255 (O9K67_16255) 3351774..3352094 - 321 WP_061494658.1 ATP-dependent Clp protease adapter ClpS -
O9K67_RS16260 (O9K67_16260) 3352423..3352644 + 222 WP_061494657.1 cold shock-like protein CspD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(29-90)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 17605.08 Da        Isoelectric Point: 5.8818

>T267216 WP_061494660.1 NZ_CP115659:3347383-3347859 [Kosakonia oryzendophytica]
MIFYRLVTHRYASEAWTGSGANLFGGRWNHKGHPAVYVASSISLAALEMLVHVHSDTVLTQYGLFSIEIPDNDIEYLDKQ
WLPPDWQENPAPLSTMDLGTAWLEANSGVALVLPSCVVPLENNAMLNPQHPTFSQLLKTVKALPFSFDARLVNQTTLR

Download         Length: 477 bp

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16381.82 Da        Isoelectric Point: 8.6778

>AT267216 WP_061494661.1 NZ_CP115659:3346943-3347386 [Kosakonia oryzendophytica]
MRTWSPDQKPAENALWRFAGFPANRGLKLVQMLNEGLPVSILDNIHEWTEMSLSDILRVTGINERNVARRKSTGRTLTPE
ESERIARLVRVVDAAVQFFGNKKMAYDWLQAPVRGLGNVAPISLIATESGALEVTDLIGRLEHGVFA

Download         Length: 444 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C4B0H3

Antitoxin

Source ID Structure

References