Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 866269..866932 Replicon chromosome
Accession NZ_CP115659
Organism Kosakonia oryzendophytica strain FY-07

Toxin (Protein)


Gene name cptA Uniprot ID A0A1C4CSM5
Locus tag O9K67_RS04200 Protein ID WP_061493250.1
Coordinates 866516..866932 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1C4CSA8
Locus tag O9K67_RS04195 Protein ID WP_061493249.1
Coordinates 866269..866535 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O9K67_RS04175 (O9K67_04175) 861815..863248 - 1434 WP_061493244.1 6-phospho-beta-glucosidase -
O9K67_RS04180 (O9K67_04180) 863365..864093 - 729 WP_061493245.1 MurR/RpiR family transcriptional regulator -
O9K67_RS04185 (O9K67_04185) 864332..864991 + 660 WP_061493246.1 hemolysin III family protein -
O9K67_RS04190 (O9K67_04190) 865037..866020 - 984 WP_061493247.1 tRNA-modifying protein YgfZ -
O9K67_RS04195 (O9K67_04195) 866269..866535 + 267 WP_061493249.1 FAD assembly factor SdhE Antitoxin
O9K67_RS04200 (O9K67_04200) 866516..866932 + 417 WP_061493250.1 protein YgfX Toxin
O9K67_RS04205 (O9K67_04205) 866951..867472 - 522 WP_061493251.1 flavodoxin FldB -
O9K67_RS04210 (O9K67_04210) 867571..868467 + 897 WP_061493252.1 site-specific tyrosine recombinase XerD -
O9K67_RS04215 (O9K67_04215) 868491..869204 + 714 WP_061493253.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
O9K67_RS04220 (O9K67_04220) 869210..870943 + 1734 WP_061493254.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16321.25 Da        Isoelectric Point: 11.4778

>T267211 WP_061493250.1 NZ_CP115659:866516-866932 [Kosakonia oryzendophytica]
VVLWQSDLRVSWRAQWLSLLLHGLVAALILLMPWPLSYTPLWLLLLSLVVFDSVRSQRRINACHGEIKLLMESRLRWQGV
EWNIVGAPWMLRSGMMLRLRREEDGRRQHLWLAADSMDAQEWRDLRRMLSQKSAQGLH

Download         Length: 417 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10478.93 Da        Isoelectric Point: 6.0701

>AT267211 WP_061493249.1 NZ_CP115659:866269-866535 [Kosakonia oryzendophytica]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKHLFVRLLESDDPDLFNWLMNHGKPQDAGLQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C4CSM5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C4CSA8

References