Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 74547..75181 Replicon chromosome
Accession NZ_CP115659
Organism Kosakonia oryzendophytica strain FY-07

Toxin (Protein)


Gene name vapC Uniprot ID A0A1C4E9S6
Locus tag O9K67_RS00320 Protein ID WP_061492456.1
Coordinates 74777..75181 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1C4E9Z4
Locus tag O9K67_RS00315 Protein ID WP_061492455.1
Coordinates 74547..74777 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O9K67_RS00290 (O9K67_00290) 70535..71437 + 903 WP_061492450.1 WYL domain-containing protein -
O9K67_RS00295 (O9K67_00295) 71465..71863 - 399 WP_061492451.1 cupin domain-containing protein -
O9K67_RS00300 (O9K67_00300) 72210..72812 - 603 WP_061492452.1 XRE family transcriptional regulator -
O9K67_RS00305 (O9K67_00305) 72858..73550 + 693 WP_061492453.1 B3/4 domain-containing protein -
O9K67_RS00310 (O9K67_00310) 73564..74445 + 882 WP_061492454.1 dihydrodipicolinate synthase family protein -
O9K67_RS00315 (O9K67_00315) 74547..74777 + 231 WP_061492455.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
O9K67_RS00320 (O9K67_00320) 74777..75181 + 405 WP_061492456.1 tRNA(fMet)-specific endonuclease VapC Toxin
O9K67_RS00325 (O9K67_00325) 75187..76245 - 1059 WP_061492457.1 AbrB family transcriptional regulator -
O9K67_RS00330 (O9K67_00330) 77122..77574 + 453 WP_061492458.1 phage tail protein -
O9K67_RS00335 (O9K67_00335) 77590..78663 + 1074 WP_061492459.1 phage tail sheath C-terminal domain-containing protein -
O9K67_RS00340 (O9K67_00340) 78681..80081 + 1401 WP_061492460.1 phage tail sheath subtilisin-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 70535..95919 25384


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15002.47 Da        Isoelectric Point: 8.5131

>T267210 WP_061492456.1 NZ_CP115659:74777-75181 [Kosakonia oryzendophytica]
MLKFMLDTNICIFTIKNKPETVRRAFNQRDGQMCISSITLMELIYGAEKSAAPEKNLRVVEGFTARLEVLPYGIDASVHT
GQLRAELAREGAPIGPYDAMIGAHARSLGLILVTNNTREFVRIPGLRLQDWTMH

Download         Length: 405 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8594.51 Da        Isoelectric Point: 4.5720

>AT267210 WP_061492455.1 NZ_CP115659:74547-74777 [Kosakonia oryzendophytica]
MEKTTLFKSNRSQAVRLPKAVALPEDVRHVDIIAVGRTRIITPSGESWDSWFDGENASADFMTAREQPGDQDREDF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1C4E9S6

Antitoxin

Source ID Structure
AlphaFold DB A0A1C4E9Z4

References