Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 549314..549967 Replicon chromosome
Accession NZ_CP115645
Organism Acinetobacter baumannii strain 2022CK-00371

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PF555_RS02615 Protein ID WP_000607070.1
Coordinates 549578..549967 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag PF555_RS02610 Protein ID WP_001288210.1
Coordinates 549314..549571 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF555_RS02590 (PF555_02590) 544830..545837 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
PF555_RS02595 (PF555_02595) 545856..546233 + 378 WP_001216380.1 50S ribosomal protein L17 -
PF555_RS02600 (PF555_02600) 546414..547904 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
PF555_RS02605 (PF555_02605) 547954..549126 - 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
PF555_RS02610 (PF555_02610) 549314..549571 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
PF555_RS02615 (PF555_02615) 549578..549967 + 390 WP_000607070.1 hypothetical protein Toxin
PF555_RS02620 (PF555_02620) 550737..551822 + 1086 WP_000049107.1 hypothetical protein -
PF555_RS02625 (PF555_02625) 551900..552466 + 567 WP_000651536.1 rhombosortase -
PF555_RS02630 (PF555_02630) 552654..554849 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15708.02 Da        Isoelectric Point: 10.3599

>T267207 WP_000607070.1 NZ_CP115645:549578-549967 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEDHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT267207 WP_001288210.1 NZ_CP115645:549314-549571 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References