Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3422280..3422933 Replicon chromosome
Accession NZ_CP115641
Organism Acinetobacter baumannii strain 2022CK-00251

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PF550_RS16335 Protein ID WP_000607070.1
Coordinates 3422280..3422669 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag PF550_RS16340 Protein ID WP_001288210.1
Coordinates 3422676..3422933 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF550_RS16320 (PF550_16320) 3417398..3419593 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
PF550_RS16325 (PF550_16325) 3419781..3420347 - 567 WP_000651536.1 rhombosortase -
PF550_RS16330 (PF550_16330) 3420425..3421510 - 1086 WP_000049107.1 hypothetical protein -
PF550_RS16335 (PF550_16335) 3422280..3422669 - 390 WP_000607070.1 hypothetical protein Toxin
PF550_RS16340 (PF550_16340) 3422676..3422933 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
PF550_RS16345 (PF550_16345) 3423121..3424293 + 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
PF550_RS16350 (PF550_16350) 3424343..3425833 - 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
PF550_RS16355 (PF550_16355) 3426014..3426391 - 378 WP_001216380.1 50S ribosomal protein L17 -
PF550_RS16360 (PF550_16360) 3426410..3427417 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15708.02 Da        Isoelectric Point: 10.3599

>T267205 WP_000607070.1 NZ_CP115641:c3422669-3422280 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEDHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT267205 WP_001288210.1 NZ_CP115641:c3422933-3422676 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References