Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3440573..3441226 Replicon chromosome
Accession NZ_CP115639
Organism Acinetobacter baumannii strain 2022CK-00241

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PF575_RS16450 Protein ID WP_000607070.1
Coordinates 3440573..3440962 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag PF575_RS16455 Protein ID WP_001288210.1
Coordinates 3440969..3441226 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF575_RS16435 (PF575_16435) 3435691..3437886 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
PF575_RS16440 (PF575_16440) 3438074..3438640 - 567 WP_000651536.1 rhombosortase -
PF575_RS16445 (PF575_16445) 3438718..3439803 - 1086 WP_000049107.1 hypothetical protein -
PF575_RS16450 (PF575_16450) 3440573..3440962 - 390 WP_000607070.1 hypothetical protein Toxin
PF575_RS16455 (PF575_16455) 3440969..3441226 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
PF575_RS16460 (PF575_16460) 3441414..3442586 + 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
PF575_RS16465 (PF575_16465) 3442636..3444126 - 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
PF575_RS16470 (PF575_16470) 3444307..3444684 - 378 WP_001216380.1 50S ribosomal protein L17 -
PF575_RS16475 (PF575_16475) 3444703..3445710 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15708.02 Da        Isoelectric Point: 10.3599

>T267204 WP_000607070.1 NZ_CP115639:c3440962-3440573 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEDHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT267204 WP_001288210.1 NZ_CP115639:c3441226-3440969 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References