267198

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 449155..449808 Replicon chromosome
Accession NZ_CP115629
Organism Acinetobacter baumannii strain 2022CK-00337

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PF547_RS02190 Protein ID WP_000607077.1
Coordinates 449419..449808 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag PF547_RS02185 Protein ID WP_001288210.1
Coordinates 449155..449412 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF547_RS02165 (PF547_02165) 444671..445678 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
PF547_RS02170 (PF547_02170) 445697..446074 + 378 WP_001216380.1 50S ribosomal protein L17 -
PF547_RS02175 (PF547_02175) 446256..447746 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
PF547_RS02180 (PF547_02180) 447795..448967 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
PF547_RS02185 (PF547_02185) 449155..449412 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
PF547_RS02190 (PF547_02190) 449419..449808 + 390 WP_000607077.1 membrane protein Toxin
PF547_RS02195 (PF547_02195) 450578..451663 + 1086 WP_000049106.1 hypothetical protein -
PF547_RS02200 (PF547_02200) 451741..452307 + 567 WP_000651538.1 rhombosortase -
PF547_RS02205 (PF547_02205) 452495..454690 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T267198 WP_000607077.1 NZ_CP115629:449419-449808 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT267198 WP_001288210.1 NZ_CP115629:449155-449412 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References