Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3477625..3478278 Replicon chromosome
Accession NZ_CP115621
Organism Acinetobacter baumannii strain 2022CK-00480

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PF364_RS16650 Protein ID WP_025467596.1
Coordinates 3477625..3478014 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag PF364_RS16655 Protein ID WP_001288210.1
Coordinates 3478021..3478278 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF364_RS16635 (PF364_16635) 3472743..3474938 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
PF364_RS16640 (PF364_16640) 3475126..3475692 - 567 WP_000651536.1 rhombosortase -
PF364_RS16645 (PF364_16645) 3475770..3476855 - 1086 WP_000049106.1 hypothetical protein -
PF364_RS16650 (PF364_16650) 3477625..3478014 - 390 WP_025467596.1 membrane protein Toxin
PF364_RS16655 (PF364_16655) 3478021..3478278 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
PF364_RS16660 (PF364_16660) 3478466..3479638 + 1173 WP_031961342.1 acyl-CoA dehydrogenase family protein -
PF364_RS16665 (PF364_16665) 3479687..3481177 - 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
PF364_RS16670 (PF364_16670) 3481359..3481736 - 378 WP_001216380.1 50S ribosomal protein L17 -
PF364_RS16675 (PF364_16675) 3481755..3482762 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15609.84 Da        Isoelectric Point: 10.3816

>T267190 WP_025467596.1 NZ_CP115621:c3478014-3477625 [Acinetobacter baumannii]
MINHLNFQLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLH

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT267190 WP_001288210.1 NZ_CP115621:c3478278-3478021 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References