267185

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DinJ
Location 4380296..4380812 Replicon chromosome
Accession NZ_CP115551
Organism Salmonella enterica subsp. enterica serovar Bispebjerg strain 20SAL-1342-3

Toxin (Protein)


Gene name relE Uniprot ID A0A3V5VNJ7
Locus tag PEE20_RS21990 Protein ID WP_000220577.1
Coordinates 4380296..4380580 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PEE20_RS21995 Protein ID WP_152210448.1
Coordinates 4380570..4380812 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PEE20_RS21975 (4375412) 4375412..4377064 + 1653 WP_270805234.1 alpha,alpha-phosphotrehalase -
PEE20_RS21980 (4377473) 4377473..4379611 + 2139 WP_000187818.1 anaerobic ribonucleoside-triphosphate reductase -
PEE20_RS21985 (4379828) 4379828..4380292 + 465 WP_017465840.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
PEE20_RS21990 (4380296) 4380296..4380580 - 285 WP_000220577.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PEE20_RS21995 (4380570) 4380570..4380812 - 243 WP_152210448.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PEE20_RS22000 (4380890) 4380890..4382803 - 1914 WP_139762420.1 BglG family transcription antiterminator -
PEE20_RS22005 (4382820) 4382820..4383560 - 741 WP_270805245.1 KDGP aldolase family protein -
PEE20_RS22010 (4383557) 4383557..4384675 - 1119 WP_151115548.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
PEE20_RS22015 (4384659) 4384659..4385792 - 1134 WP_000459930.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-65)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10912.71 Da        Isoelectric Point: 9.8739

>T267185 WP_000220577.1 NZ_CP115551:c4380580-4380296 [Salmonella enterica subsp. enterica serovar Bispebjerg]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARLNDLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8989.40 Da        Isoelectric Point: 5.0651

>AT267185 WP_152210448.1 NZ_CP115551:c4380812-4380570 [Salmonella enterica subsp. enterica serovar Bispebjerg]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVVETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V5VNJ7

Antitoxin

Source ID Structure

References