267170

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 4098169..4098804 Replicon chromosome
Accession NZ_CP115484
Organism Paenibacillus sp. SYP-B4298

Toxin (Protein)


Gene name mazF Uniprot ID A0A934MKW6
Locus tag PDL12_RS17145 Protein ID WP_020618872.1
Coordinates 4098169..4098519 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PDL12_RS17150 Protein ID WP_028563293.1
Coordinates 4098523..4098804 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PDL12_RS17130 4094260..4094766 + 507 WP_270165652.1 hypothetical protein -
PDL12_RS17135 4095013..4096323 + 1311 WP_270165654.1 ParB/RepB/Spo0J family partition protein -
PDL12_RS17140 4096355..4097896 + 1542 WP_270165656.1 DUF4901 domain-containing protein -
PDL12_RS17145 4098169..4098519 - 351 WP_020618872.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PDL12_RS17150 4098523..4098804 - 282 WP_028563293.1 CopG family ribbon-helix-helix protein Antitoxin
PDL12_RS17155 4099186..4100367 - 1182 WP_270172629.1 alanine racemase -
PDL12_RS17160 4100523..4101713 - 1191 WP_270165660.1 outer membrane lipoprotein carrier protein LolA -
PDL12_RS17165 4102021..4102668 - 648 WP_270165662.1 ATP-binding cassette domain-containing protein -
PDL12_RS17170 4102665..4103423 - 759 WP_270165664.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12892.81 Da        Isoelectric Point: 4.8728

>T267170 WP_020618872.1 NZ_CP115484:c4098519-4098169 [Paenibacillus sp. SYP-B4298]
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAATHEFDRDSVILLEQI
RTIDKQRLTDKITHLDDETMRKVDEALQISVGLIDF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10725.32 Da        Isoelectric Point: 8.5844

>AT267170 WP_028563293.1 NZ_CP115484:c4098804-4098523 [Paenibacillus sp. SYP-B4298]
VANMQNTKRIMISLPDHLLQEVDGIVARENSNRSEFIRQAMRLYLIERKKRQIRESMQRGYLEMAKINLNMASEAFQAEE
DADSTLGRLVSGV

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References