Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 2552333..2553000 Replicon chromosome
Accession NZ_CP115465
Organism Brevundimonas sp. NIBR11

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O5O43_RS12870 Protein ID WP_271084292.1
Coordinates 2552584..2553000 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O5O43_RS12865 Protein ID WP_271084291.1
Coordinates 2552333..2552584 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O5O43_RS12850 (KKHFBJBL_02556) 2547480..2548529 - 1050 WP_271084288.1 DUF2125 domain-containing protein -
O5O43_RS12855 (KKHFBJBL_02557) 2548773..2549207 + 435 WP_271084289.1 VOC family protein -
O5O43_RS12860 (KKHFBJBL_02558) 2549332..2552235 - 2904 WP_271084290.1 ATP-dependent DNA helicase -
O5O43_RS12865 (KKHFBJBL_02559) 2552333..2552584 + 252 WP_271084291.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O5O43_RS12870 (KKHFBJBL_02560) 2552584..2553000 + 417 WP_271084292.1 type II toxin-antitoxin system VapC family toxin Toxin
O5O43_RS12875 (KKHFBJBL_02561) 2552997..2555489 + 2493 WP_271084293.1 ligase-associated DNA damage response DEXH box helicase -
O5O43_RS12880 (KKHFBJBL_02562) 2555486..2556229 + 744 WP_271084294.1 ligase-associated DNA damage response endonuclease PdeM -
O5O43_RS12885 (KKHFBJBL_02563) 2556226..2556642 - 417 WP_271084295.1 DUF3429 domain-containing protein -
O5O43_RS12890 (KKHFBJBL_02564) 2556642..2557457 - 816 WP_271084296.1 TIGR02186 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-67)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15727.91 Da        Isoelectric Point: 5.0132

>T267168 WP_271084292.1 NZ_CP115465:2552584-2553000 [Brevundimonas sp. NIBR11]
MFLLDTNAISEPKRARPDPGVVAWLGEQLLSDLHLSVITVGELRRGIVRLEPSRRRDDLDFWLEDMILRYDERILPVDLD
VTERWASIAEAQRAAGRVSEMTDELIAATAHVHGLTVVTRNVRHFENTGCRVLSPWSE

Download         Length: 417 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9461.60 Da        Isoelectric Point: 5.8819

>AT267168 WP_271084291.1 NZ_CP115465:2552333-2552584 [Brevundimonas sp. NIBR11]
MSWSVAKAKDNLSEVIRRSRTEGPQEISLHGEAAAVVLSAEDFRRLKDPRASRDFKDWLLNGPSLEGVDLERDRRPAREI
DPF

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References