Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 2552333..2553000 Replicon chromosome
Accession NZ_CP115465
Organism Brevundimonas sp. NIBR11

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O5O43_RS12870 Protein ID WP_271084292.1
Coordinates 2552584..2553000 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O5O43_RS12865 Protein ID WP_271084291.1
Coordinates 2552333..2552584 (+) Length 84 a.a.

Genomic Context


O5O43_RS12855O5O43_RS12865O5O43_RS12870O5O43_RS12875O5O43_RS12880O5O43_RS12850O5O43_RS12860O5O43_RS12885O5O43_RS12890
Location: 2548773..2549207 (435 bp)
Type: Others
Protein ID: WP_271084289.1
Location: 2552333..2552584 (252 bp)
Type: Antitoxin
Protein ID: WP_271084291.1
Location: 2552584..2553000 (417 bp)
Type: Toxin
Protein ID: WP_271084292.1
Location: 2552997..2555489 (2493 bp)
Type: Others
Protein ID: WP_271084293.1
Location: 2555486..2556229 (744 bp)
Type: Others
Protein ID: WP_271084294.1
Location: 2547480..2548529 (1050 bp)
Type: Others
Protein ID: WP_271084288.1
Location: 2549332..2552235 (2904 bp)
Type: Others
Protein ID: WP_271084290.1
Location: 2556226..2556642 (417 bp)
Type: Others
Protein ID: WP_271084295.1
Location: 2556642..2557457 (816 bp)
Type: Others
Protein ID: WP_271084296.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
O5O43_RS12850 (KKHFBJBL_02556)2547480..2548529-1050WP_271084288.1DUF2125 domain-containing protein-
O5O43_RS12855 (KKHFBJBL_02557)2548773..2549207+435WP_271084289.1VOC family protein-
O5O43_RS12860 (KKHFBJBL_02558)2549332..2552235-2904WP_271084290.1ATP-dependent DNA helicase-
O5O43_RS12865 (KKHFBJBL_02559)2552333..2552584+252WP_271084291.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
O5O43_RS12870 (KKHFBJBL_02560)2552584..2553000+417WP_271084292.1type II toxin-antitoxin system VapC family toxinToxin
O5O43_RS12875 (KKHFBJBL_02561)2552997..2555489+2493WP_271084293.1ligase-associated DNA damage response DEXH box helicase-
O5O43_RS12880 (KKHFBJBL_02562)2555486..2556229+744WP_271084294.1ligase-associated DNA damage response endonuclease PdeM-
O5O43_RS12885 (KKHFBJBL_02563)2556226..2556642-417WP_271084295.1DUF3429 domain-containing protein-
O5O43_RS12890 (KKHFBJBL_02564)2556642..2557457-816WP_271084296.1TIGR02186 family protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-123)

Antitoxin

(2-67)


Sequences


Toxin        


Download         Length: 139 a.a.        Molecular weight: 15727.91 Da        Isoelectric Point: 5.0132

>T267168 WP_271084292.1 NZ_CP115465:2552584-2553000 [Brevundimonas sp. NIBR11]
MFLLDTNAISEPKRARPDPGVVAWLGEQLLSDLHLSVITVGELRRGIVRLEPSRRRDDLDFWLEDMILRYDERILPVDLD
VTERWASIAEAQRAAGRVSEMTDELIAATAHVHGLTVVTRNVRHFENTGCRVLSPWSE

Download         Length: 417 bp


Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9461.60 Da        Isoelectric Point: 5.8819

>AT267168 WP_271084291.1 NZ_CP115465:2552333-2552584 [Brevundimonas sp. NIBR11]
MSWSVAKAKDNLSEVIRRSRTEGPQEISLHGEAAAVVLSAEDFRRLKDPRASRDFKDWLLNGPSLEGVDLERDRRPAREI
DPF

Download         Length: 252 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References