Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3864063..3864687 Replicon chromosome
Accession NZ_CP115464
Organism Brevundimonas sp. NIBR10

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag O5K39_RS18810 Protein ID WP_271145125.1
Coordinates 3864063..3864389 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag O5K39_RS18815 Protein ID WP_271145126.1
Coordinates 3864379..3864687 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O5K39_RS18795 (KOAAANKH_03738) 3861765..3862223 - 459 WP_271145122.1 TIGR02300 family protein -
O5K39_RS18800 (KOAAANKH_03739) 3862353..3863675 + 1323 WP_271145123.1 3-phosphoshikimate 1-carboxyvinyltransferase -
O5K39_RS18805 (KOAAANKH_03740) 3863672..3864058 + 387 WP_271145124.1 RidA family protein -
O5K39_RS18810 (KOAAANKH_03741) 3864063..3864389 + 327 WP_271145125.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O5K39_RS18815 (KOAAANKH_03742) 3864379..3864687 + 309 WP_271145126.1 putative addiction module antidote protein Antitoxin
O5K39_RS18820 (KOAAANKH_03743) 3864687..3865331 + 645 WP_271145127.1 (d)CMP kinase -
O5K39_RS18825 (KOAAANKH_03744) 3865499..3867202 + 1704 WP_271145128.1 30S ribosomal protein S1 -
O5K39_RS18830 (KOAAANKH_03745) 3867480..3867770 + 291 WP_271145129.1 integration host factor subunit beta -
O5K39_RS18835 (KOAAANKH_03746) 3867856..3868275 + 420 WP_271145130.1 large-conductance mechanosensitive channel protein MscL -
O5K39_RS18840 (KOAAANKH_03747) 3868266..3869399 - 1134 WP_271145131.1 N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(12-103)

Antitoxin

Uncharacterized protein HI1420

(7-94)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11875.54 Da        Isoelectric Point: 10.1482

>T267167 WP_271145125.1 NZ_CP115464:3864063-3864389 [Brevundimonas sp. NIBR10]
MSPIDDNRSINVELSPRFVAWRDGLRDRLAVAKIASRILGLKRGHWGDVKPVGGGVSELRIHSGPGYRIYLTRRGADWIV
LLCGGDKDSQARDIAAAKSMASEFRDAD

Download         Length: 327 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11187.85 Da        Isoelectric Point: 4.0948

>AT267167 WP_271145126.1 NZ_CP115464:3864379-3864687 [Brevundimonas sp. NIBR10]
MPIETIPFDAADWLETPEMVEAFLIESFESAFELDDPGMISEALGVVARARGMTRMAEDANLSRTALYRALSDQGRPELA
TIFKVMQALGLRLAPVRVDTAA

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References