Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3238316..3238962 Replicon chromosome
Accession NZ_CP115464
Organism Brevundimonas sp. NIBR10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O5K39_RS15880 Protein ID WP_271144574.1
Coordinates 3238316..3238705 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O5K39_RS15885 Protein ID WP_271144575.1
Coordinates 3238702..3238962 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O5K39_RS15865 (KOAAANKH_03155) 3233464..3234450 - 987 WP_271144571.1 M20/M25/M40 family metallo-hydrolase -
O5K39_RS15870 (KOAAANKH_03156) 3234570..3236885 + 2316 WP_271144572.1 NAD-dependent DNA ligase LigA -
O5K39_RS15875 (KOAAANKH_03157) 3237264..3238253 - 990 WP_271144573.1 aldo/keto reductase -
O5K39_RS15880 (KOAAANKH_03158) 3238316..3238705 - 390 WP_271144574.1 type II toxin-antitoxin system VapC family toxin Toxin
O5K39_RS15885 (KOAAANKH_03159) 3238702..3238962 - 261 WP_271144575.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
O5K39_RS15890 (KOAAANKH_03160) 3238997..3240826 - 1830 WP_271144576.1 aminopeptidase P family protein -
O5K39_RS15895 (KOAAANKH_03161) 3240889..3241791 - 903 WP_271144577.1 enoyl-CoA hydratase-related protein -
O5K39_RS15900 (KOAAANKH_03162) 3241871..3242308 + 438 WP_271144578.1 HIT family protein -
O5K39_RS15905 (KOAAANKH_03163) 3242305..3242658 - 354 WP_271144579.1 DMT family protein -
O5K39_RS15915 (KOAAANKH_03165) 3242916..3243548 + 633 WP_271144580.1 TetR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(2-79)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14380.43 Da        Isoelectric Point: 4.7687

>T267165 WP_271144574.1 NZ_CP115464:c3238705-3238316 [Brevundimonas sp. NIBR10]
MIVDTSALVAIINSEPEAERFLSILIREPRVRLSAVTYFEFGMVVDNWRDEPTSLKVDRLLSGVEAEIVEVDADTARLAR
AAYRRFGKKNHPAKLNFGDCFAYALAKQTGEPLLFKGDDFAQTDIVSAV

Download         Length: 390 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9722.11 Da        Isoelectric Point: 4.5915

>AT267165 WP_271144575.1 NZ_CP115464:c3238962-3238702 [Brevundimonas sp. NIBR10]
MLNIKNPETHRLAKELAARRGESLTGVVTYALREQLAREPEPVKKKATMEELLALVDEIRKAAPPEFFETEDPTAEFYDP
ETGLPI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References