Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 155169..155724 Replicon chromosome
Accession NZ_CP115464
Organism Brevundimonas sp. NIBR10

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag O5K39_RS00810 Protein ID WP_271145413.1
Coordinates 155431..155724 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag O5K39_RS00805 Protein ID WP_271145412.1
Coordinates 155169..155414 (+) Length 82 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O5K39_RS00790 (KOAAANKH_00160) 151127..152956 + 1830 WP_271145409.1 cation:proton antiporter -
O5K39_RS00795 (KOAAANKH_00161) 153245..153901 + 657 WP_271145410.1 TetR/AcrR family transcriptional regulator -
O5K39_RS00800 (KOAAANKH_00162) 153968..155086 - 1119 WP_271145411.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
O5K39_RS00805 (KOAAANKH_00163) 155169..155414 + 246 WP_271145412.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
O5K39_RS00810 155431..155724 + 294 WP_271145413.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O5K39_RS00815 (KOAAANKH_00164) 155721..156470 + 750 WP_271145414.1 DUF72 domain-containing protein -
O5K39_RS00820 (KOAAANKH_00165) 156554..157624 + 1071 WP_271145415.1 NAD(P)-dependent alcohol dehydrogenase -
O5K39_RS00825 (KOAAANKH_00166) 157658..158287 - 630 WP_271145416.1 maleylacetoacetate isomerase -
O5K39_RS00830 (KOAAANKH_00167) 158290..158982 - 693 WP_271145417.1 fumarylacetoacetate hydrolase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-88)

Antitoxin

(3-68)


Sequences


Toxin        


Download         Length: 98 a.a.        Molecular weight: 11080.59 Da        Isoelectric Point: 5.0911

>T267163 WP_271145413.1 NZ_CP115464:155431-155724 [Brevundimonas sp. NIBR10]
MSLAARQDLSTIYRHGVEAFGQRQADRYIDGLLETLDLIADFPEMARVRDSLNPPACVHGHRRHVIVYDLLADEIVLIVR
IRHALEDWQGLSGDMEQ

Download         Length: 294 bp


Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9293.41 Da        Isoelectric Point: 6.3270

>AT267163 WP_271145412.1 NZ_CP115464:155169-155414 [Brevundimonas sp. NIBR10]
MATMNISLPDQMKAWVEAQSADGRYSNSSDYVRDLIRREQIRAEKIANMQRLVDEGRASGVSDQSPRQIIDEIRAELRQR
A

Download         Length: 246 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References