Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParST/RES-Xre
Location 4145998..4146899 Replicon chromosome
Accession NZ_CP115463
Organism Caulobacter sp. NIBR1757

Toxin (Protein)


Gene name ParT Uniprot ID -
Locus tag O5I81_RS19905 Protein ID WP_271066605.1
Coordinates 4145998..4146477 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name ParS Uniprot ID -
Locus tag O5I81_RS19910 Protein ID WP_271066606.1
Coordinates 4146474..4146899 (-) Length 142 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O5I81_RS19875 (AMEJIAPC_03936) 4141069..4141557 - 489 WP_271066599.1 hypothetical protein -
O5I81_RS19880 (AMEJIAPC_03937) 4141744..4143324 + 1581 WP_271066600.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase -
O5I81_RS19885 (AMEJIAPC_03938) 4143633..4144397 + 765 WP_271066601.1 prolyl oligopeptidase family serine peptidase -
O5I81_RS19890 (AMEJIAPC_03939) 4144491..4144823 + 333 WP_271066602.1 hypothetical protein -
O5I81_RS19895 (AMEJIAPC_03940) 4144871..4145215 - 345 WP_271066603.1 barstar family protein -
O5I81_RS19900 (AMEJIAPC_03941) 4145373..4145909 + 537 WP_271066604.1 hypothetical protein -
O5I81_RS19905 (AMEJIAPC_03942) 4145998..4146477 - 480 WP_271066605.1 RES family NAD+ phosphorylase Toxin
O5I81_RS19910 (AMEJIAPC_03943) 4146474..4146899 - 426 WP_271066606.1 DUF2384 domain-containing protein Antitoxin
O5I81_RS19915 (AMEJIAPC_03944) 4147061..4151896 - 4836 WP_271066607.1 NAD-glutamate dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(4-153)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(80-138)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 16801.02 Da        Isoelectric Point: 5.1340

>T267162 WP_271066605.1 NZ_CP115463:c4146477-4145998 [Caulobacter sp. NIBR1757]
VSRRLWRIAADTPDYEADDLSGAGARITGGRWNAPGSAVVYTSASIALACLETVVHFNAGGLPFNRYLVAIDIPDSVWAA
AQRETPASLPVGWDAEPAGRVSIGLGTDWIASGASALLIVPSVLVPEEINILINPTHPDAGGITAGKIRKWTYDPRLSR

Download         Length: 480 bp

Antitoxin


Download         Length: 142 a.a.        Molecular weight: 14952.13 Da        Isoelectric Point: 5.8506

>AT267162 WP_271066606.1 NZ_CP115463:c4146899-4146474 [Caulobacter sp. NIBR1757]
MSYIDIYRAEPVVRIGMIKAGVPAAQAKRIFHDLAISQGAGLSALKLSAATVNRKASQDATLSADESERVIGVAKLVGQL
QAMVEESGDPQGFDAPAWLSRWLREPLPALGGQAPMTLLDTMEGQSLVSRTLSQIQSGAYA

Download         Length: 426 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References