Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 531828..532387 Replicon plasmid pKN1
Accession NZ_CP115457
Organism Sphingobium yanoikuyae strain CC4533

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PAE53_RS24885 Protein ID WP_270093862.1
Coordinates 532094..532387 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PAE53_RS24880 Protein ID WP_214867854.1
Coordinates 531828..532106 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAE53_RS24860 (PAE53_24860) 527390..528931 + 1542 WP_270093858.1 peptidase S10 -
PAE53_RS24865 (PAE53_24865) 528931..530457 + 1527 WP_270093859.1 peptidase S10 -
PAE53_RS24870 (PAE53_24870) 530656..531246 - 591 WP_270093860.1 nucleotidyltransferase family protein -
PAE53_RS24875 (PAE53_24875) 531272..531595 - 324 WP_270093861.1 hypothetical protein -
PAE53_RS24880 (PAE53_24880) 531828..532106 + 279 WP_214867854.1 CopG family ribbon-helix-helix protein Antitoxin
PAE53_RS24885 (PAE53_24885) 532094..532387 + 294 WP_270093862.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PAE53_RS24890 (PAE53_24890) 532497..532780 + 284 Protein_483 hypothetical protein -
PAE53_RS24895 (PAE53_24895) 532811..533020 - 210 WP_270094157.1 hypothetical protein -
PAE53_RS24900 (PAE53_24900) 533423..533755 - 333 WP_270093863.1 hypothetical protein -
PAE53_RS24905 (PAE53_24905) 534110..534298 - 189 WP_270093864.1 hypothetical protein -
PAE53_RS24910 (PAE53_24910) 534669..534935 + 267 WP_270093865.1 hypothetical protein -
PAE53_RS24915 (PAE53_24915) 534969..535211 + 243 WP_270093866.1 hypothetical protein -
PAE53_RS24920 (PAE53_24920) 535443..535649 - 207 WP_270093867.1 hypothetical protein -
PAE53_RS24925 (PAE53_24925) 535708..535932 + 225 WP_270093868.1 hypothetical protein -
PAE53_RS24930 (PAE53_24930) 535929..536366 + 438 WP_270093869.1 PIN domain-containing protein -
PAE53_RS24935 (PAE53_24935) 536366..537284 + 919 Protein_492 HEPN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..647509 647509


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10750.33 Da        Isoelectric Point: 8.4278

>T267155 WP_270093862.1 NZ_CP115457:532094-532387 [Sphingobium yanoikuyae]
VSRLIWTPNALADVQRLYGWLLPKDAEAATRAVATIRAGVRILAASPRIGRPVEDMDPDYREKLIDFGNSGYVALYRLDG
ETVAILAVRHQKEAGYP

Download         Length: 294 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10599.88 Da        Isoelectric Point: 5.6165

>AT267155 WP_214867854.1 NZ_CP115457:531828-532106 [Sphingobium yanoikuyae]
MAAATSIKLDDALKGRVQHLAEVRRRSSHWIMREAIAQYVEREEKREAFRQDAIRAWDEYQQTGLHLTLEEADAWLAKLE
AGEDAEPPKCHG

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References