Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2438409..2438857 Replicon chromosome
Accession NZ_CP115456
Organism Sphingobium yanoikuyae strain CC4533

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PAE53_RS11520 Protein ID WP_270090923.1
Coordinates 2438585..2438857 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PAE53_RS11515 Protein ID WP_097385691.1
Coordinates 2438409..2438585 (+) Length 59 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAE53_RS11500 (PAE53_11500) 2433920..2436838 + 2919 WP_270090920.1 excinuclease ABC subunit UvrA -
PAE53_RS11505 (PAE53_11505) 2436999..2437595 - 597 WP_270090921.1 hypothetical protein -
PAE53_RS11510 (PAE53_11510) 2437592..2438146 - 555 WP_270090922.1 hypothetical protein -
PAE53_RS11515 (PAE53_11515) 2438409..2438585 + 177 WP_097385691.1 stability determinant Antitoxin
PAE53_RS11520 (PAE53_11520) 2438585..2438857 + 273 WP_270090923.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PAE53_RS11525 (PAE53_11525) 2438995..2440191 + 1197 WP_270090924.1 hypothetical protein -
PAE53_RS11530 (PAE53_11530) 2440303..2440518 + 216 WP_004207726.1 cold-shock protein -
PAE53_RS11535 (PAE53_11535) 2440580..2441182 - 603 WP_037491660.1 hypothetical protein -
PAE53_RS11540 (PAE53_11540) 2441319..2441525 + 207 WP_010336653.1 hypothetical protein -
PAE53_RS11545 (PAE53_11545) 2441705..2442088 + 384 WP_004207729.1 glycine zipper 2TM domain-containing protein -
PAE53_RS11550 (PAE53_11550) 2442203..2443135 - 933 WP_097384049.1 FAD-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10310.91 Da        Isoelectric Point: 7.3992

>T267153 WP_270090923.1 NZ_CP115456:2438585-2438857 [Sphingobium yanoikuyae]
MLPLIWHVAALDDLERIVDFIEAQNPAAAERIGNAIRHVAERLPDHPYLYRSGRVPGTREALVTPNYVIVYRVTAIIEIL
AVRHTRQQYP

Download         Length: 273 bp

Antitoxin


Download         Length: 59 a.a.        Molecular weight: 6556.34 Da        Isoelectric Point: 4.4797

>AT267153 WP_097385691.1 NZ_CP115456:2438409-2438585 [Sphingobium yanoikuyae]
MTKLTPIESEFASTEEAEAYDAWFRATVEARMASDQPGIPHDEAMARMQAIIDRRKQG

Download         Length: 177 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References