Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1118102..1118938 Replicon chromosome
Accession NZ_CP115456
Organism Sphingobium yanoikuyae strain CC4533

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag PAE53_RS05445 Protein ID WP_270092854.1
Coordinates 1118423..1118938 (+) Length 172 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag PAE53_RS05440 Protein ID WP_066769168.1
Coordinates 1118102..1118401 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAE53_RS05425 (PAE53_05425) 1115092..1116513 - 1422 WP_270092851.1 conjugal transfer protein TraH -
PAE53_RS05430 (PAE53_05430) 1116567..1117142 - 576 WP_270092852.1 hypothetical protein -
PAE53_RS05435 (PAE53_05435) 1117142..1117996 - 855 WP_270092853.1 conjugal transfer protein TraF -
PAE53_RS05440 (PAE53_05440) 1118102..1118401 + 300 WP_066769168.1 DUF1778 domain-containing protein Antitoxin
PAE53_RS05445 (PAE53_05445) 1118423..1118938 + 516 WP_270092854.1 GNAT family N-acetyltransferase Toxin
PAE53_RS05450 (PAE53_05450) 1118962..1119567 - 606 WP_066769172.1 S26 family signal peptidase -
PAE53_RS05455 (PAE53_05455) 1119539..1120420 - 882 WP_270092855.1 TrbC family F-type conjugative pilus assembly protein -
PAE53_RS05460 (PAE53_05460) 1120392..1121516 - 1125 WP_270093638.1 conjugal transfer protein TraN -
PAE53_RS05465 (PAE53_05465) 1121513..1123369 - 1857 WP_270093639.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1077635..1212390 134755


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(39-149)

Antitoxin

Vibrio phage ICP1, Orf50

(18-93)


Sequences

Toxin        


Download         Length: 172 a.a.        Molecular weight: 18407.13 Da        Isoelectric Point: 7.0403

>T267152 WP_270092854.1 NZ_CP115456:1118423-1118938 [Sphingobium yanoikuyae]
MTRRRVTPPERLNADHCVDGFENGRHASLDHWLAERALASEGASARTYVVCDADRPGHVAGYYTITTAMEERAALPTARL
RRGMPDKVPLLLIARLAVDVGFQGLGLGADLLADALRRCAAASEIAGVRAVIVHAIDDAAVGFYERHGFIASPLGERVLL
MPIEAVRALQG

Download         Length: 516 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11158.86 Da        Isoelectric Point: 8.8053

>AT267152 WP_066769168.1 NZ_CP115456:1118102-1118401 [Sphingobium yanoikuyae]
MAQARSDRSASPRKDDVIQIRAAAELKALLSRAALLRGQKLSEFMLASARREAEAAILDQRTFFLDAESHEQFLAILDAP
PAPSLKLEELMKRQPLWDR

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References