Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1099296..1099954 Replicon chromosome
Accession NZ_CP115456
Organism Sphingobium yanoikuyae strain CC4533

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PAE53_RS05340 Protein ID WP_270092839.1
Coordinates 1099296..1099703 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PAE53_RS05345 Protein ID WP_270092840.1
Coordinates 1099700..1099954 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PAE53_RS05315 (PAE53_05315) 1095263..1095928 - 666 WP_270092834.1 OmpW family outer membrane protein -
PAE53_RS05320 (PAE53_05320) 1096659..1097135 + 477 WP_270092835.1 RNA polymerase sigma factor -
PAE53_RS05325 (PAE53_05325) 1097527..1097841 + 315 WP_270092836.1 helix-turn-helix transcriptional regulator -
PAE53_RS05330 (PAE53_05330) 1097878..1098243 - 366 WP_270092837.1 hypothetical protein -
PAE53_RS05335 (PAE53_05335) 1098362..1099285 - 924 WP_270092838.1 HEPN domain-containing protein -
PAE53_RS05340 (PAE53_05340) 1099296..1099703 - 408 WP_270092839.1 type II toxin-antitoxin system VapC family toxin Toxin
PAE53_RS05345 (PAE53_05345) 1099700..1099954 - 255 WP_270092840.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PAE53_RS05350 (PAE53_05350) 1100251..1100367 + 117 Protein_1057 type II toxin-antitoxin system prevent-host-death family antitoxin -
PAE53_RS05355 (PAE53_05355) 1100377..1100661 - 285 WP_270093764.1 hypothetical protein -
PAE53_RS05360 (PAE53_05360) 1101373..1101564 - 192 WP_270092841.1 hypothetical protein -
PAE53_RS05365 (PAE53_05365) 1102343..1103713 + 1371 WP_088184704.1 IS1380 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1077635..1212390 134755


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-125)

Antitoxin

Antitoxin VapB-like

(5-83)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15030.04 Da        Isoelectric Point: 4.5348

>T267151 WP_270092839.1 NZ_CP115456:c1099703-1099296 [Sphingobium yanoikuyae]
VIVDTSALVAILYREEEAEDFADLIQRADICRMSVATYLELTLVIEKQLGPEGTRHAENFIRRAGIQIEPVTVEQGLIAR
QAFFDFGKGRHSAALNYGDCFPYALAKAVDEPLLFKGNDFSQTDVESALPRARPQ

Download         Length: 408 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9387.71 Da        Isoelectric Point: 7.2045

>AT267151 WP_270092840.1 NZ_CP115456:c1099954-1099700 [Sphingobium yanoikuyae]
MGGTLNIKDPEAHRLAQAIAQETGEPMTRVVVEALRDRLSRIERQRERASVGELLGIADRAARLVVKPYPKHGEELYDEN
GLPK

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References