267150

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 6417585..6418213 Replicon chromosome
Accession NZ_CP115450
Organism Kitasatospora sp. HUAS 3-15

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O1G21_RS28790 Protein ID WP_270147750.1
Coordinates 6417803..6418213 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O1G21_RS28785 Protein ID WP_270147748.1
Coordinates 6417585..6417806 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1G21_RS28765 (O1G21_28765) 6412700..6414475 + 1776 WP_270147744.1 DEAD/DEAH box helicase -
O1G21_RS28770 (O1G21_28770) 6415065..6415460 + 396 Protein_5653 ricin-type beta-trefoil lectin domain protein -
O1G21_RS28775 (O1G21_28775) 6415529..6416377 - 849 WP_270147745.1 helix-turn-helix transcriptional regulator -
O1G21_RS28780 (O1G21_28780) 6416491..6417504 + 1014 WP_270147747.1 hypothetical protein -
O1G21_RS28785 (O1G21_28785) 6417585..6417806 + 222 WP_270147748.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
O1G21_RS28790 (O1G21_28790) 6417803..6418213 + 411 WP_270147750.1 PIN domain-containing protein Toxin
O1G21_RS28795 (O1G21_28795) 6418227..6418955 - 729 WP_270147752.1 sirohydrochlorin chelatase -
O1G21_RS28800 (O1G21_28800) 6418966..6419859 - 894 WP_270147754.1 ABC transporter permease -
O1G21_RS28805 (O1G21_28805) 6419846..6420646 - 801 WP_270147756.1 ABC transporter ATP-binding protein -
O1G21_RS28810 (O1G21_28810) 6420765..6421916 - 1152 WP_270147758.1 aliphatic sulfonate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(3-43)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15233.26 Da        Isoelectric Point: 5.5523

>T267150 WP_270147750.1 NZ_CP115450:6417803-6418213 [Kitasatospora sp. HUAS 3-15]
VIYLIDTSALFRLMRDPKLKTAWYDAIDAGSIASCYPQRAELLFSARDGREYDEISELFAELYPDVSVPKNAGRWIDMVQ
RRMALAGRHRSASAVDLMIAATAAHHGLTVLHDDADYRTVARYATDLSEHSILDCA

Download         Length: 411 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8587.68 Da        Isoelectric Point: 7.4051

>AT267150 WP_270147748.1 NZ_CP115450:6417585-6417806 [Kitasatospora sp. HUAS 3-15]
MSVTQIDIDDEALERAMALAGVRTKKEAVNLALRFYAERQERAARISRHFERAQHWEALEHAERMHRAEKDAR

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References