267147

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-PHD
Location 3307046..3307728 Replicon chromosome
Accession NZ_CP115450
Organism Kitasatospora sp. HUAS 3-15

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O1G21_RS14500 Protein ID WP_270143941.1
Coordinates 3307046..3307450 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O1G21_RS14505 Protein ID WP_270143943.1
Coordinates 3307447..3307728 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1G21_RS14490 (O1G21_14490) 3303009..3304499 + 1491 WP_270143937.1 maltokinase -
O1G21_RS14495 (O1G21_14495) 3304598..3307009 + 2412 WP_270143939.1 1,4-alpha-glucan branching protein GlgB -
O1G21_RS14500 (O1G21_14500) 3307046..3307450 - 405 WP_270143941.1 type II toxin-antitoxin system VapC family toxin Toxin
O1G21_RS14505 (O1G21_14505) 3307447..3307728 - 282 WP_270143943.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
O1G21_RS14510 (O1G21_14510) 3307906..3310065 + 2160 WP_270143945.1 phosphate acetyltransferase -
O1G21_RS14515 (O1G21_14515) 3310166..3311389 + 1224 WP_270143947.1 acetate kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-50)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14876.08 Da        Isoelectric Point: 5.6761

>T267147 WP_270143941.1 NZ_CP115450:c3307450-3307046 [Kitasatospora sp. HUAS 3-15]
MIYLDSCALLKFIKPEPETAALRAWREALPDGTELITSELARLEITRTLLRAGLSHQLVPYHVDQALRGAYQVDLSSAVL
ARALAYRTPRLGSLDALHLASAEPFRAELTDFVTYDRELARAAEELGFPVTAPR

Download         Length: 405 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10249.70 Da        Isoelectric Point: 4.4410

>AT267147 WP_270143943.1 NZ_CP115450:c3307728-3307447 [Kitasatospora sp. HUAS 3-15]
METMGLRELNQNPSKAVARVRAGATIVVTDRGRPVMRLVPETEPESTLERMVAAGEVTPPAEQGMPELALDLLPDVGSLS
DLLIEERNRERDR

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References