Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazE-MazF
Location 2587811..2588385 Replicon chromosome
Accession NZ_CP115396
Organism Hymenobacter yonginensis strain KCTC 22745

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag O9Z63_RS11245 Protein ID WP_270125301.1
Coordinates 2587811..2588065 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag O9Z63_RS11250 Protein ID WP_270125302.1
Coordinates 2588059..2588385 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O9Z63_RS11230 (O9Z63_11230) 2584096..2585421 + 1326 WP_270125299.1 trigger factor -
O9Z63_RS11235 (O9Z63_11235) 2585533..2586243 + 711 WP_044016820.1 ATP-dependent Clp protease proteolytic subunit -
O9Z63_RS11240 (O9Z63_11240) 2586458..2587681 + 1224 WP_044016818.1 ATP-dependent Clp protease ATP-binding subunit ClpX -
O9Z63_RS11245 (O9Z63_11245) 2587811..2588065 + 255 WP_270125301.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Toxin
O9Z63_RS11250 (O9Z63_11250) 2588059..2588385 + 327 WP_270125302.1 type II toxin-antitoxin system PemK/MazF family toxin Antitoxin
O9Z63_RS11255 (O9Z63_11255) 2588558..2588896 - 339 WP_270125303.1 hypothetical protein -
O9Z63_RS11260 (O9Z63_11260) 2588906..2590015 - 1110 WP_270125305.1 lipid-A-disaccharide synthase -
O9Z63_RS11265 (O9Z63_11265) 2590119..2590535 - 417 WP_044016814.1 6-carboxytetrahydropterin synthase -
O9Z63_RS11270 (O9Z63_11270) 2590676..2591674 - 999 WP_270125307.1 iron ABC transporter permease -
O9Z63_RS11275 (O9Z63_11275) 2591777..2592685 - 909 WP_270125309.1 helical backbone metal receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

mRNA interferase PemK-like

(3-106)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9407.56 Da        Isoelectric Point: 4.2213

>T267085 WP_270125301.1 NZ_CP115396:2587811-2588065 [Hymenobacter yonginensis]
MQTRIIRVGNSQGIVLPKKLLQQYHLSGEVDLRATPDGLLITPVLRPARQDWDARFAAATAAGEEPEEEMLEGFADASED
EWTW

Download         Length: 255 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12287.18 Da        Isoelectric Point: 8.2745

>AT267085 WP_270125302.1 NZ_CP115396:2588059-2588385 [Hymenobacter yonginensis]
MVAISRFEVWLVNLDPTQGSEINKTRPCVIISPNELNRHLRTVIIAALTSTRRNYPSRVNCEFEAKEGQVALDQIRSVDK
TRLMRKLGTLPDSAAQEICAVLQELFQY

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References