Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2331867..2332845 Replicon chromosome
Accession NZ_CP115307
Organism Bacillus cereus strain BC-01

Toxin (Protein)


Gene name spoIISA Uniprot ID W8Y388
Locus tag GVV68_RS16090 Protein ID WP_000624977.1
Coordinates 2331867..2332604 (+) Length 246 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag GVV68_RS16095 Protein ID WP_000237820.1
Coordinates 2332717..2332845 (+) Length 43 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GVV68_RS16065 (GVV68_16065) 2327483..2327890 + 408 WP_000063589.1 VOC family protein -
GVV68_RS16070 (GVV68_16070) 2327903..2328292 + 390 Protein_2287 SAM-dependent methyltransferase -
GVV68_RS16075 (GVV68_16075) 2328450..2330135 - 1686 WP_061655972.1 alpha-keto acid decarboxylase family protein -
GVV68_RS16080 (GVV68_16080) 2330243..2330725 + 483 WP_000191888.1 MarR family winged helix-turn-helix transcriptional regulator -
GVV68_RS16085 (GVV68_16085) 2330892..2331629 + 738 WP_000594152.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
GVV68_RS16090 (GVV68_16090) 2331867..2332604 + 738 WP_000624977.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
GVV68_RS16095 (GVV68_16095) 2332717..2332845 + 129 WP_000237820.1 hypothetical protein Antitoxin
GVV68_RS16100 (GVV68_16100) 2332918..2333094 + 177 WP_000852632.1 stage II sporulation protein SB -
GVV68_RS16105 (GVV68_16105) 2333113..2333502 - 390 WP_000713867.1 YxeA family protein -
GVV68_RS16110 (GVV68_16110) 2333714..2335183 + 1470 WP_000287515.1 beta-Ala-His dipeptidase -
GVV68_RS16115 (GVV68_16115) 2335429..2336238 + 810 WP_000678508.1 papain-like cysteine protease family protein -
GVV68_RS16120 (GVV68_16120) 2336264..2336866 + 603 WP_000517260.1 hypothetical protein -
GVV68_RS16125 (GVV68_16125) 2337107..2337358 - 252 WP_000827560.1 LuxR C-terminal-related transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(10-243)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 246 a.a.        Molecular weight: 28307.03 Da        Isoelectric Point: 8.2998

>T267084 WP_000624977.1 NZ_CP115307:2331867-2332604 [Bacillus cereus]
MISNIRIGLFVLAIVFVVLVFFYWKNEELYEEKKQRIRKTWYGLFIISVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYTKSLNAFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSIIVPLEHIEQLNEQKAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK

Download         Length: 738 bp

Antitoxin


Download         Length: 43 a.a.        Molecular weight: 5010.41 Da        Isoelectric Point: 3.9798

>AT267084 WP_000237820.1 NZ_CP115307:2332717-2332845 [Bacillus cereus]
VVKDYDNDFFKENNEDTTDFSLIKGDTLQQVEELEEELKRKS

Download         Length: 129 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB W8Y388

Antitoxin

Source ID Structure

References