Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 640513..641476 Replicon chromosome
Accession NZ_CP115303
Organism Bacillus tropicus strain JMT105-2

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag AVT_RS03445 Protein ID WP_131102745.1
Coordinates 640739..641476 (-) Length 246 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag AVT_RS03440 Protein ID WP_029438356.1
Coordinates 640513..640641 (-) Length 43 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AVT_RS03415 (AVT_03415) 635655..636022 - 368 Protein_682 D-alanyl-D-alanine carboxypeptidase -
AVT_RS03420 (AVT_03420) 636490..637149 - 660 WP_087963884.1 CatB-related O-acetyltransferase -
AVT_RS03425 (AVT_03425) 637605..638075 + 471 WP_087963883.1 DUF5065 family protein -
AVT_RS03430 (AVT_03430) 638587..640056 - 1470 WP_270185206.1 beta-Ala-His dipeptidase -
AVT_RS03435 (AVT_03435) 640264..640440 - 177 WP_087963880.1 stage II sporulation protein SB -
AVT_RS03440 (AVT_03440) 640513..640641 - 129 WP_029438356.1 hypothetical protein Antitoxin
AVT_RS03445 (AVT_03445) 640739..641476 - 738 WP_131102745.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
AVT_RS03450 (AVT_03450) 641663..642400 - 738 WP_087963878.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
AVT_RS03455 (AVT_03455) 642567..643049 - 483 WP_087963877.1 MarR family winged helix-turn-helix transcriptional regulator -
AVT_RS03460 (AVT_03460) 643156..644841 + 1686 WP_131102165.1 alpha-keto acid decarboxylase family protein -
AVT_RS03465 (AVT_03465) 644963..645745 - 783 WP_270185207.1 class I SAM-dependent methyltransferase -
AVT_RS03470 (AVT_03470) 646034..646441 - 408 WP_078985373.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(9-243)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 246 a.a.        Molecular weight: 28415.26 Da        Isoelectric Point: 8.2638

>T267081 WP_131102745.1 NZ_CP115303:c641476-640739 [Bacillus tropicus]
VISNIRIGLFILAIVFLLLIFFYWKNEELYEEKKQRIRKTWYGLFIISVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYTKSLNAFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSIMIPLEYIEQLNEQKAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFIK

Download         Length: 738 bp

Antitoxin


Download         Length: 43 a.a.        Molecular weight: 5025.42 Da        Isoelectric Point: 3.9150

>AT267081 WP_029438356.1 NZ_CP115303:c640641-640513 [Bacillus tropicus]
VIKDYDNDFFKEDNEDTTDFSLIKGDTLQQVEELEEELKRKS

Download         Length: 129 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References