267078

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1274436..1275353 Replicon chromosome
Accession NZ_CP115185
Organism Bacillus velezensis strain 26.3

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag O9K61_RS06775 Protein ID WP_032866111.1
Coordinates 1274607..1275353 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag O9K61_RS06770 Protein ID WP_003154807.1
Coordinates 1274436..1274606 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O9K61_RS06735 (O9K61_06735) 1269669..1271291 + 1623 WP_032866113.1 pyocin knob domain-containing protein -
O9K61_RS06740 (O9K61_06740) 1271304..1271675 + 372 WP_020955692.1 XkdW family protein -
O9K61_RS06745 (O9K61_06745) 1271680..1271877 + 198 WP_020955693.1 XkdX family protein -
O9K61_RS06750 (O9K61_06750) 1271934..1272695 + 762 WP_020955694.1 hypothetical protein -
O9K61_RS06755 (O9K61_06755) 1272747..1273010 + 264 WP_032866112.1 hemolysin XhlA family protein -
O9K61_RS06760 (O9K61_06760) 1273024..1273287 + 264 WP_003154813.1 phage holin -
O9K61_RS06765 (O9K61_06765) 1273301..1274179 + 879 WP_020955695.1 N-acetylmuramoyl-L-alanine amidase -
O9K61_RS06770 (O9K61_06770) 1274436..1274606 - 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
O9K61_RS06775 (O9K61_06775) 1274607..1275353 - 747 WP_032866111.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
O9K61_RS06780 (O9K61_06780) 1275457..1276455 - 999 WP_020955696.1 inorganic phosphate transporter -
O9K61_RS06785 (O9K61_06785) 1276468..1277085 - 618 WP_003154804.1 DUF47 domain-containing protein -
O9K61_RS06790 (O9K61_06790) 1277371..1278687 - 1317 WP_007610842.1 amino acid permease -
O9K61_RS06795 (O9K61_06795) 1279010..1279960 + 951 WP_012117369.1 ring-cleaving dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29095.60 Da        Isoelectric Point: 4.7755

>T267078 WP_032866111.1 NZ_CP115185:c1275353-1274607 [Bacillus velezensis]
MLMFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT267078 WP_003154807.1 NZ_CP115185:c1274606-1274436 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References