Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1813217..1814007 Replicon chromosome
Accession NZ_CP115182
Organism Diaphorobacter sp. ED-3

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag PCQ86_RS08960 Protein ID WP_270175309.1
Coordinates 1813507..1814007 (+) Length 167 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag PCQ86_RS08955 Protein ID WP_270175308.1
Coordinates 1813217..1813510 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCQ86_RS08935 1810393..1811049 + 657 WP_011805663.1 OmpA family protein -
PCQ86_RS08940 1811129..1811842 + 714 WP_270175307.1 bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG -
PCQ86_RS08945 1811839..1812516 + 678 WP_047349155.1 HAD-IA family hydrolase -
PCQ86_RS08955 1813217..1813510 + 294 WP_270175308.1 DUF1778 domain-containing protein Antitoxin
PCQ86_RS08960 1813507..1814007 + 501 WP_270175309.1 GNAT family N-acetyltransferase Toxin
PCQ86_RS08965 1814172..1814456 + 285 WP_270175310.1 helix-turn-helix transcriptional regulator -
PCQ86_RS08970 1814469..1814906 - 438 WP_270175311.1 hypothetical protein -
PCQ86_RS08975 1815182..1815811 + 630 WP_270175312.1 integrase arm-type DNA-binding domain-containing protein -
PCQ86_RS08980 1816007..1816255 + 249 WP_270175313.1 helix-turn-helix transcriptional regulator -
PCQ86_RS08990 1816566..1817585 - 1020 WP_015913677.1 class 1 fructose-bisphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(40-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-96)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 18362.21 Da        Isoelectric Point: 10.0337

>T267071 WP_270175309.1 NZ_CP115182:1813507-1814007 [Diaphorobacter sp. ED-3]
VTLRAPEPLAAQHRLEGFDCGKPALNDWLLRHARQAQGSGSAKTFVVAEDDGRVAGYFSLTVGQVDTLEAPERIRKGMGQ
YPLPVVILARLAVSVADQGRGIGFGLLQDAIRRTMLIAEQAGIRAMLTHPIDEEAARFYTRFGFIASPLRDQQLLLLLKD
ARRWVR

Download         Length: 501 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10775.25 Da        Isoelectric Point: 5.1035

>AT267071 WP_270175308.1 NZ_CP115182:1813217-1813510 [Diaphorobacter sp. ED-3]
MTAVASSPSARSARLGLRATPEQEVVLRRAAEVAHKSLTDFILDSACLAAEQTLLDQRLFMVSGSQYQALMDLLDRPEQA
NEDLRDLFARKAPWDTK

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References