Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 44614..45122 Replicon chromosome
Accession NZ_CP115175
Organism Homoserinibacter sp. YIM 151385

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag OF852_RS00225 Protein ID WP_271119810.1
Coordinates 44859..45122 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OF852_RS00220 Protein ID WP_271119809.1
Coordinates 44614..44862 (+) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OF852_RS00200 (OF852_00200) 40321..40893 - 573 WP_271119806.1 CGNR zinc finger domain-containing protein -
OF852_RS00205 (OF852_00205) 40971..42284 + 1314 WP_271119807.1 EamA family transporter -
OF852_RS00210 (OF852_00210) 42281..43246 + 966 WP_271119808.1 DMT family transporter -
OF852_RS00215 (OF852_00215) 43296..44579 + 1284 WP_271121187.1 ATP phosphoribosyltransferase regulatory subunit -
OF852_RS00220 (OF852_00220) 44614..44862 + 249 WP_271119809.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OF852_RS00225 (OF852_00225) 44859..45122 + 264 WP_271119810.1 Txe/YoeB family addiction module toxin Toxin
OF852_RS00230 (OF852_00230) 45205..46485 + 1281 WP_271119811.1 phosphopyruvate hydratase -
OF852_RS00235 (OF852_00235) 46607..47113 + 507 WP_271119812.1 septum formation initiator family protein -
OF852_RS00240 (OF852_00240) 47110..47625 + 516 WP_271119813.1 DUF501 domain-containing protein -
OF852_RS00245 (OF852_00245) 47670..48872 + 1203 WP_271121188.1 S8 family serine peptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(7-87)

Antitoxin

(2-71)


Sequences


Toxin        


Download         Length: 88 a.a.        Molecular weight: 10273.72 Da        Isoelectric Point: 8.5038

>T267067 WP_271119810.1 NZ_CP115175:44859-45122 [Homoserinibacter sp. YIM 151385]
MTRRLVWVDEAWEDYLHWQGQDRKTLKRINLLIADVRRGDPFEGIGKPEPLKHALAGAWSRRIDDVNRLVYIADAESVTI
LQARYHY

Download         Length: 264 bp


Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8915.12 Da        Isoelectric Point: 5.1255

>AT267067 WP_271119809.1 NZ_CP115175:44614-44862 [Homoserinibacter sp. YIM 151385]
MAITASEARADLFGLIERVNLDHIEVEITSKRGAAVIMSKDEYDALIETAHLLRSPANARRLLRALDSARAGAGTEREPI
EG

Download         Length: 249 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References