Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 4303937..4304454 Replicon chromosome
Accession NZ_CP115174
Organism Sphingomonas sp. PAMB00755

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PBT88_RS20390 Protein ID WP_270077102.1
Coordinates 4303937..4304203 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PBT88_RS20395 Protein ID WP_270077103.1
Coordinates 4304200..4304454 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PBT88_RS20370 (PBT88_20370) 4299200..4299934 + 735 WP_270077099.1 sterol desaturase family protein -
PBT88_RS20375 (PBT88_20375) 4299944..4300423 - 480 WP_270079333.1 hypothetical protein -
PBT88_RS20380 (PBT88_20380) 4300734..4302665 + 1932 WP_270077100.1 phosphomethylpyrimidine synthase ThiC -
PBT88_RS20385 (PBT88_20385) 4302695..4303882 - 1188 WP_270077101.1 hypothetical protein -
PBT88_RS20390 (PBT88_20390) 4303937..4304203 - 267 WP_270077102.1 Txe/YoeB family addiction module toxin Toxin
PBT88_RS20395 (PBT88_20395) 4304200..4304454 - 255 WP_270077103.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PBT88_RS20400 (PBT88_20400) 4304492..4305202 - 711 WP_270077104.1 uracil-DNA glycosylase -
PBT88_RS20405 (PBT88_20405) 4305300..4305620 + 321 WP_270077105.1 hypothetical protein -
PBT88_RS20410 (PBT88_20410) 4305637..4305858 - 222 WP_270077106.1 hypothetical protein -
PBT88_RS20415 (PBT88_20415) 4305982..4306533 + 552 WP_270077107.1 hypothetical protein -
PBT88_RS20420 (PBT88_20420) 4306569..4308194 - 1626 WP_270077108.1 NAD(P)/FAD-dependent oxidoreductase -
PBT88_RS20425 (PBT88_20425) 4308195..4309415 - 1221 WP_270077109.1 aromatic ring-hydroxylating dioxygenase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10177.57 Da        Isoelectric Point: 9.7893

>T267066 WP_270077102.1 NZ_CP115174:c4304203-4303937 [Sphingomonas sp. PAMB00755]
VKITFSSVAWDHYLYWQAEDAKVLARLNALLKECQRDPFRGTGKPEPLGGNLSGWWSRRINSEHRLVYRVAGKGDRQALE
VAACRYHY

Download         Length: 267 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9284.60 Da        Isoelectric Point: 4.6128

>AT267066 WP_270077103.1 NZ_CP115174:c4304454-4304200 [Sphingomonas sp. PAMB00755]
MTALSFSDARANLKAVMDRAVADRAPISITRQKAEGVVMISQSEWDSIQETLYLLRSPKNAEMLLRGIAELDAGKGEEHE
LIEP

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References