267065

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 3925951..3926459 Replicon chromosome
Accession NZ_CP115174
Organism Sphingomonas sp. PAMB00755

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag PBT88_RS18395 Protein ID WP_270076748.1
Coordinates 3926214..3926459 (-) Length 82 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag PBT88_RS18390 Protein ID WP_270076747.1
Coordinates 3925951..3926217 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PBT88_RS18360 (PBT88_18360) 3920961..3921404 - 444 WP_270076741.1 DUF2501 domain-containing protein -
PBT88_RS18365 (PBT88_18365) 3921531..3922988 - 1458 WP_270076742.1 AMP nucleosidase -
PBT88_RS18370 (PBT88_18370) 3923153..3924088 + 936 WP_270076743.1 hypothetical protein -
PBT88_RS18375 (PBT88_18375) 3924100..3924666 - 567 WP_270076744.1 DUF6456 domain-containing protein -
PBT88_RS18380 (PBT88_18380) 3924759..3925325 + 567 WP_270076745.1 helix-turn-helix transcriptional regulator -
PBT88_RS18385 (PBT88_18385) 3925358..3925693 - 336 WP_270076746.1 hypothetical protein -
PBT88_RS18390 (PBT88_18390) 3925951..3926217 - 267 WP_270076747.1 BrnA antitoxin family protein Antitoxin
PBT88_RS18395 (PBT88_18395) 3926214..3926459 - 246 WP_270076748.1 BrnT family toxin Toxin
PBT88_RS18405 (PBT88_18405) 3927055..3927669 - 615 WP_270076749.1 winged helix DNA-binding protein -
PBT88_RS18410 (PBT88_18410) 3927768..3927953 + 186 WP_270076750.1 hypothetical protein -
PBT88_RS18415 (PBT88_18415) 3928097..3928495 - 399 WP_270076751.1 flagellar protein FliS -
PBT88_RS18420 (PBT88_18420) 3928525..3930270 - 1746 WP_270076752.1 flagellar filament capping protein FliD -
PBT88_RS18425 (PBT88_18425) 3930345..3930734 - 390 WP_270076753.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-76)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(16-85)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 8824.26 Da        Isoelectric Point: 10.7407

>T267065 WP_270076748.1 NZ_CP115174:c3926459-3926214 [Sphingomonas sp. PAMB00755]
VIIVWDEPKREANLAKHGIDFADIGESFFASAIVRPSRAGRFAAFGELNGKIAVIFLALGTEGISIISARPASRKERRLM
P

Download         Length: 246 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9616.79 Da        Isoelectric Point: 6.3191

>AT267065 WP_270076747.1 NZ_CP115174:c3926217-3925951 [Sphingomonas sp. PAMB00755]
MTEPKYTQADLDAVSDNPEWTAADFAEAKPFAEAFPELAQSKRGPQRKPTKVSTTIRLSPDVLDRFKAGGPGWQSRIDDA
LRKAVGLG

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References