267063

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-RHH
Location 313003..313598 Replicon chromosome
Accession NZ_CP115174
Organism Sphingomonas sp. PAMB00755

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PBT88_RS01565 Protein ID WP_270077502.1
Coordinates 313003..313389 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PBT88_RS01570 Protein ID WP_270077503.1
Coordinates 313383..313598 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PBT88_RS01560 (PBT88_01560) 311299..312981 - 1683 WP_270079137.1 recombinase family protein -
PBT88_RS01565 (PBT88_01565) 313003..313389 - 387 WP_270077502.1 type II toxin-antitoxin system VapC family toxin Toxin
PBT88_RS01570 (PBT88_01570) 313383..313598 - 216 WP_270077503.1 ribbon-helix-helix protein, CopG family Antitoxin
PBT88_RS01575 (PBT88_01575) 313675..313869 - 195 WP_270077504.1 hypothetical protein -
PBT88_RS01580 (PBT88_01580) 313850..314092 - 243 WP_270077505.1 AlpA family phage regulatory protein -
PBT88_RS01585 (PBT88_01585) 314474..315502 - 1029 WP_270077506.1 hypothetical protein -
PBT88_RS01590 (PBT88_01590) 316202..316819 + 618 WP_270077507.1 hypothetical protein -
PBT88_RS01595 (PBT88_01595) 316812..317390 + 579 WP_270077508.1 sigma-70 family RNA polymerase sigma factor -
PBT88_RS01600 (PBT88_01600) 317463..317720 - 258 WP_270077509.1 conjugal transfer protein TraD -
PBT88_RS01605 (PBT88_01605) 317734..318060 - 327 WP_270077510.1 conjugal transfer protein TraD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 311322..362247 50925


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-106)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-40)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14165.31 Da        Isoelectric Point: 5.1663

>T267063 WP_270077502.1 NZ_CP115174:c313389-313003 [Sphingomonas sp. PAMB00755]
MVGALFDTNILIDHLNAIPQARKEIARYGDPAISIVTWMEVMVGAGAELVEPTRRFLDGFAVVELDNDIAERAVSLRRSH
RIKLPDAIIWATAQVAGRILVTRNTKDFPTDDPGIREPYAIWGSVSPI

Download         Length: 387 bp

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8297.30 Da        Isoelectric Point: 6.4659

>AT267063 WP_270077503.1 NZ_CP115174:c313598-313383 [Sphingomonas sp. PAMB00755]
MRALVDMSDSQVEALDVLARRKRRSRASLIRAAIDDYLARHRHQQVEDGFGLWGERELDGLAYQEQVRGEW

Download         Length: 216 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References