267061

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 3831667..3832666 Replicon chromosome
Accession NZ_CP115160
Organism Algoriphagus sp. TR-M9

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag PBT90_RS16205 Protein ID WP_264807560.1
Coordinates 3832103..3832666 (+) Length 188 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag PBT90_RS16200 Protein ID WP_264807559.1
Coordinates 3831667..3832113 (+) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PBT90_RS16185 (PBT90_16185) 3827067..3827897 - 831 WP_264807556.1 universal stress protein -
PBT90_RS16190 (PBT90_16190) 3828109..3829704 + 1596 WP_264807557.1 M14 family metallopeptidase -
PBT90_RS16195 (PBT90_16195) 3829808..3831535 + 1728 WP_264807558.1 M14 family metallopeptidase -
PBT90_RS16200 (PBT90_16200) 3831667..3832113 + 447 WP_264807559.1 helix-turn-helix domain-containing protein Antitoxin
PBT90_RS16205 (PBT90_16205) 3832103..3832666 + 564 WP_264807560.1 PIN domain-containing protein Toxin
PBT90_RS16210 (PBT90_16210) 3832702..3833502 - 801 WP_264807561.1 LexA family transcriptional regulator -
PBT90_RS16215 (PBT90_16215) 3833572..3834720 + 1149 WP_264807562.1 DNA polymerase IV -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-114)

Antitoxin

Helix-turn-helix domain, group 17

(78-124)


Sequences

Toxin        


Download         Length: 188 a.a.        Molecular weight: 21668.93 Da        Isoelectric Point: 5.9262

>T267061 WP_264807560.1 NZ_CP115160:3832103-3832666 [Algoriphagus sp. TR-M9]
MIHSVRFICVLDTNVIYPIDIRDLLFWFAFYDLFTPKWSKHIFDEWLEVMIRKGVKRTEAFKRVSKAHQAFPDALVENYE
PIISSINLPDEKDKHVLAAAIKANANIIVTNNLKDFPPEYLATFGLSVKNADDFITDTIDLNQDLALKAFRTLVMNRQNP
DLNEFEVLDRLRNCGLHDSANYLHSLL

Download         Length: 564 bp

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16946.59 Da        Isoelectric Point: 5.7729

>AT267061 WP_264807559.1 NZ_CP115160:3831667-3832113 [Algoriphagus sp. TR-M9]
MEDLIRPTKEDQKAAMKSYDTLASMLKNIHSDYPEIEIEETQERIKIPLNALKLLAEILKETSQGKPVSIVPTATEITTQ
AAAELLGCSRPHLVKLLEQGEINFIKIGKHRRIKYEDVIEYKKKLKAEQRRLLIEIIQSDEESGLYDS

Download         Length: 447 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References