Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2726412..2726615 Replicon chromosome
Accession NZ_CP115150
Organism Enterobacter hormaechei subsp. xiangfangensis strain MDCL 3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2726505..2726608 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2726412..2726615 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUY00_RS12970 (MUY00_12970) 2722949..2723611 - 663 WP_058656540.1 exodeoxyribonuclease X -
MUY00_RS12975 (MUY00_12975) 2723636..2724286 - 651 WP_058656541.1 carbon-nitrogen hydrolase family protein -
MUY00_RS12980 (MUY00_12980) 2724398..2724628 - 231 WP_003859784.1 DNA polymerase III subunit theta -
MUY00_RS12985 (MUY00_12985) 2724766..2725137 + 372 WP_003859785.1 CopC domain-containing protein YobA -
MUY00_RS12990 (MUY00_12990) 2725139..2726008 + 870 WP_003859786.1 copper homeostasis membrane protein CopD -
MUY00_RS12995 (MUY00_12995) 2726025..2726363 + 339 WP_003859787.1 YebY family protein -
- 2726412..2726615 - 204 - - Antitoxin
- 2726505..2726608 + 104 - - Toxin
MUY00_RS13000 (MUY00_13000) 2726686..2727771 - 1086 WP_058691373.1 phage integrase Arm DNA-binding domain-containing protein -
MUY00_RS13005 (MUY00_13005) 2727740..2728012 - 273 WP_023300430.1 excisionase -
MUY00_RS13010 (MUY00_13010) 2728215..2728427 + 213 WP_045617122.1 hypothetical protein -
MUY00_RS13015 (MUY00_13015) 2728433..2728672 - 240 WP_058656543.1 DUF4222 domain-containing protein -
MUY00_RS13020 (MUY00_13020) 2728672..2728890 - 219 WP_058656544.1 TraR/DksA family transcriptional regulator -
MUY00_RS13025 (MUY00_13025) 2729209..2729427 - 219 WP_032621601.1 hypothetical protein -
MUY00_RS13030 (MUY00_13030) 2729424..2729975 - 552 WP_022651070.1 phage N-6-adenine-methyltransferase -
MUY00_RS13035 (MUY00_13035) 2729972..2730124 - 153 WP_022651071.1 DUF1317 family protein -
MUY00_RS13040 (MUY00_13040) 2730121..2730549 - 429 WP_022651072.1 hypothetical protein -
MUY00_RS13045 (MUY00_13045) 2730546..2731226 - 681 WP_022651073.1 YqaJ viral recombinase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gtrB / gtrA 2660018..2791876 131858


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T267050 NZ_CP115150:2726505-2726608 [Enterobacter hormaechei subsp. xiangfangensis]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 204 bp

>AT267050 NZ_CP115150:c2726615-2726412 [Enterobacter hormaechei subsp. xiangfangensis]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTAAAAGTG
GTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References