Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1686371..1687028 Replicon chromosome
Accession NZ_CP115150
Organism Enterobacter hormaechei subsp. xiangfangensis strain MDCL 3

Toxin (Protein)


Gene name cptA Uniprot ID A0A0A6GSQ9
Locus tag MUY00_RS08095 Protein ID WP_022649305.1
Coordinates 1686618..1687028 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag MUY00_RS08090 Protein ID WP_003863437.1
Coordinates 1686371..1686637 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUY00_RS08070 (MUY00_08070) 1681803..1683236 - 1434 WP_003863430.1 6-phospho-beta-glucosidase BglA -
MUY00_RS08075 (MUY00_08075) 1683353..1684084 - 732 WP_003863431.1 MurR/RpiR family transcriptional regulator -
MUY00_RS08080 (MUY00_08080) 1684351..1685010 + 660 WP_058656477.1 hemolysin III family protein -
MUY00_RS08085 (MUY00_08085) 1685096..1686076 - 981 WP_058656478.1 tRNA-modifying protein YgfZ -
MUY00_RS08090 (MUY00_08090) 1686371..1686637 + 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
MUY00_RS08095 (MUY00_08095) 1686618..1687028 + 411 WP_022649305.1 protein YgfX Toxin
MUY00_RS08100 (MUY00_08100) 1687030..1687551 - 522 WP_003863440.1 flavodoxin FldB -
MUY00_RS08105 (MUY00_08105) 1687653..1688549 + 897 WP_003863442.1 site-specific tyrosine recombinase XerD -
MUY00_RS08110 (MUY00_08110) 1688578..1689291 + 714 WP_003863443.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
MUY00_RS08115 (MUY00_08115) 1689297..1691030 + 1734 WP_003863445.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16321.21 Da        Isoelectric Point: 11.4775

>T267048 WP_022649305.1 NZ_CP115150:1686618-1687028 [Enterobacter hormaechei subsp. xiangfangensis]
VVLWQSDLRVSWRSQWMSLLLHGLVAAMVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMIGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT267048 WP_003863437.1 NZ_CP115150:1686371-1686637 [Enterobacter hormaechei subsp. xiangfangensis]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0A6GSQ9

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References