Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 2003369..2003916 Replicon chromosome
Accession NZ_CP114976
Organism Denitrificimonas caeni strain CE14

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag O6P33_RS09475 Protein ID WP_269817539.1
Coordinates 2003369..2003671 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag O6P33_RS09480 Protein ID WP_100689219.1
Coordinates 2003659..2003916 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O6P33_RS09460 (O6P33_09460) 2000219..2000512 - 294 WP_269817536.1 DUF1883 domain-containing protein -
O6P33_RS09465 (O6P33_09465) 2000748..2001890 + 1143 WP_269817537.1 MFS transporter -
O6P33_RS09470 (O6P33_09470) 2002226..2003179 + 954 WP_269817538.1 NAD(P)-dependent oxidoreductase -
O6P33_RS09475 (O6P33_09475) 2003369..2003671 - 303 WP_269817539.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O6P33_RS09480 (O6P33_09480) 2003659..2003916 - 258 WP_100689219.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O6P33_RS09485 (O6P33_09485) 2004046..2005671 - 1626 WP_269817540.1 DUF2326 domain-containing protein -
O6P33_RS09490 (O6P33_09490) 2005665..2005886 - 222 WP_269817541.1 hypothetical protein -
O6P33_RS09495 (O6P33_09495) 2005883..2006686 - 804 WP_269817542.1 HNH endonuclease signature motif containing protein -
O6P33_RS09500 (O6P33_09500) 2007293..2007754 - 462 WP_269817543.1 hypothetical protein -
O6P33_RS09505 (O6P33_09505) 2007751..2008107 - 357 WP_269817544.1 hypothetical protein -
O6P33_RS09510 (O6P33_09510) 2008257..2008673 - 417 WP_269819461.1 DUF1090 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11608.28 Da        Isoelectric Point: 4.4755

>T267044 WP_269817539.1 NZ_CP114976:c2003671-2003369 [Denitrificimonas caeni]
MAEIIWTEPALHELDALAEYVALDNPEAASHLVEKVFDKIESLENFPQSGRVPPGLPNSVYREVVVTPCRIFYREDDKRV
LILYVMREERQLRAYMLESS

Download         Length: 303 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9906.46 Da        Isoelectric Point: 9.5343

>AT267044 WP_100689219.1 NZ_CP114976:c2003916-2003659 [Denitrificimonas caeni]
MKVELVTNLKRQATKILADLRLSKEPVLITEHGQPSAYLVDVQDYEFMQRRLELLEGLSRGERAVLEGRTYSQSEAREKM
SKWLK

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References