Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1443695..1443966 Replicon chromosome
Accession NZ_CP114891
Organism Escherichia coli strain CM2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1443825..1443928 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1443695..1443966 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O6Q44_RS06975 1440250..1440912 - 663 WP_000944256.1 exodeoxyribonuclease X -
O6Q44_RS06980 1440936..1441592 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
O6Q44_RS06985 1441694..1441924 - 231 WP_000916763.1 DNA polymerase III subunit theta -
O6Q44_RS06990 1442063..1442437 + 375 WP_000168747.1 CopC domain-containing protein YobA -
O6Q44_RS06995 1442441..1443313 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
O6Q44_RS07000 1443326..1443667 + 342 WP_000976476.1 YebY family protein -
- 1443695..1443966 - 272 - - Antitoxin
- 1443825..1443928 + 104 - - Toxin
O6Q44_RS07005 1444063..1444719 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
O6Q44_RS07010 1444720..1444911 - 192 WP_000457842.1 YebW family protein -
O6Q44_RS07015 1445016..1445252 - 237 WP_001295499.1 YebV family protein -
O6Q44_RS07020 1445370..1446809 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T266901 NZ_CP114891:1443825-1443928 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT266901 NZ_CP114891:c1443966-1443695 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References