Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 5942822..5943444 Replicon chromosome
Accession NZ_CP114886
Organism Endozoicomonas sp. GU-1 strain Ap1-3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O2T12_RS24760 Protein ID WP_269676652.1
Coordinates 5942822..5943211 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O2T12_RS24765 Protein ID WP_269671894.1
Coordinates 5943223..5943444 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2T12_RS24745 (O2T12_24745) 5939504..5939686 - 183 WP_269676651.1 hypothetical protein -
O2T12_RS24750 (O2T12_24750) 5939756..5939851 - 96 WP_269675989.1 hypothetical protein -
O2T12_RS24755 (O2T12_24755) 5940086..5942482 - 2397 WP_269671892.1 exonuclease domain-containing protein -
O2T12_RS24760 (O2T12_24760) 5942822..5943211 - 390 WP_269676652.1 PIN domain-containing protein Toxin
O2T12_RS24765 (O2T12_24765) 5943223..5943444 - 222 WP_269671894.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
O2T12_RS24770 (O2T12_24770) 5943519..5943842 + 324 WP_269671895.1 hypothetical protein -
O2T12_RS24775 (O2T12_24775) 5943963..5945216 + 1254 WP_269671896.1 ISL3 family transposase -
O2T12_RS24780 (O2T12_24780) 5945660..5945935 - 276 WP_163370563.1 type II toxin-antitoxin system RelE/ParE family toxin -
O2T12_RS24785 (O2T12_24785) 5945932..5946180 - 249 WP_257266787.1 ribbon-helix-helix protein, CopG family -
O2T12_RS24790 (O2T12_24790) 5946566..5947156 + 591 WP_269671897.1 nucleotidyltransferase domain-containing protein -
O2T12_RS24795 (O2T12_24795) 5947153..5947338 + 186 WP_269671898.1 hypothetical protein -
O2T12_RS24800 (O2T12_24800) 5947447..5947848 - 402 WP_269671899.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 5940086..5978176 38090


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-120)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14501.48 Da        Isoelectric Point: 6.6383

>T266888 WP_269676652.1 NZ_CP114886:c5943211-5942822 [Endozoicomonas sp. GU-1]
MVDTDICIAVLKHNRPVIDKFIEHQGKVYVSSISCYELQFGIEKGDPEHRQGKESKLSFFLEGVNVIDFDGAAARESAKV
REELQRGQQIGAYDTLLAAHARSRGMVMVTHNQREFSRVPGLQLADWLG

Download         Length: 390 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8622.85 Da        Isoelectric Point: 4.3449

>AT266888 WP_269671894.1 NZ_CP114886:c5943444-5943223 [Endozoicomonas sp. GU-1]
METSVFFNNKTQAVRIPKELAFPDTVKRVMVRKEGKAIILTPIEDYWETFLAMEPIDDFPEREQPACQDREDF

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References