Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 2932589..2933172 Replicon chromosome
Accession NZ_CP114886
Organism Endozoicomonas sp. GU-1 strain Ap1-3

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag O2T12_RS12395 Protein ID WP_269674120.1
Coordinates 2932918..2933172 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag O2T12_RS12390 Protein ID WP_269674119.1
Coordinates 2932589..2932921 (-) Length 111 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2T12_RS12380 (O2T12_12380) 2928724..2932080 + 3357 WP_269674117.1 hypothetical protein -
O2T12_RS12385 (O2T12_12385) 2932073..2932525 - 453 WP_269674118.1 deaminase -
O2T12_RS12390 (O2T12_12390) 2932589..2932921 - 333 WP_269674119.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
O2T12_RS12395 (O2T12_12395) 2932918..2933172 - 255 WP_269674120.1 type II toxin-antitoxin system HicA family toxin Toxin
O2T12_RS12400 (O2T12_12400) 2933336..2934550 - 1215 WP_269674121.1 multidrug effflux MFS transporter -
O2T12_RS12405 (O2T12_12405) 2934806..2935783 + 978 WP_269677206.1 potassium channel family protein -
O2T12_RS12410 (O2T12_12410) 2936205..2936639 + 435 WP_269674123.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(23-74)

Antitoxin

Uncharacterised protein family HicB

(55-105)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9466.98 Da        Isoelectric Point: 11.1073

>T266882 WP_269674120.1 NZ_CP114886:c2933172-2932918 [Endozoicomonas sp. GU-1]
MKKKHATTLRKLFARPVSGSIHWADIESLFLGLGAKVEEREGSRIKVVLFGEVRIFHRPHPSPDTDKGAVASIRRWLENH
GVTP

Download         Length: 255 bp

Antitoxin


Download         Length: 111 a.a.        Molecular weight: 12119.59 Da        Isoelectric Point: 4.6135

>AT266882 WP_269674119.1 NZ_CP114886:c2932921-2932589 [Endozoicomonas sp. GU-1]
MINQMNINGYTAIITYDPDIDLFRGEFIGLNGGADFYAADVKSLHQEGKVSLKVFLEACQEEGIEPRKSFSGKLNLRIDP
DLHESASVAAAASNRSLNQFINDALRQSLN

Download         Length: 333 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References