Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2785601..2786132 Replicon chromosome
Accession NZ_CP114886
Organism Endozoicomonas sp. GU-1 strain Ap1-3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag O2T12_RS11710 Protein ID WP_163373295.1
Coordinates 2785601..2785888 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag O2T12_RS11715 Protein ID WP_163373296.1
Coordinates 2785878..2786132 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2T12_RS11675 (O2T12_11675) 2781137..2781448 - 312 WP_269673999.1 HigA family addiction module antitoxin -
O2T12_RS11680 (O2T12_11680) 2781724..2782185 - 462 WP_269674000.1 hypothetical protein -
O2T12_RS11685 (O2T12_11685) 2782236..2782847 - 612 WP_269674001.1 hypothetical protein -
O2T12_RS11690 (O2T12_11690) 2782884..2783855 - 972 WP_269674002.1 IS66 family transposase -
O2T12_RS11695 (O2T12_11695) 2783866..2784507 - 642 WP_269674003.1 transposase -
O2T12_RS11700 (O2T12_11700) 2784639..2785007 - 369 WP_269674004.1 DUF3768 domain-containing protein -
O2T12_RS11705 (O2T12_11705) 2785133..2785609 + 477 WP_269674005.1 hypothetical protein -
O2T12_RS11710 (O2T12_11710) 2785601..2785888 - 288 WP_163373295.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O2T12_RS11715 (O2T12_11715) 2785878..2786132 - 255 WP_163373296.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2T12_RS11720 (O2T12_11720) 2786207..2788068 + 1862 Protein_2292 phage terminase large subunit family protein -
O2T12_RS11725 (O2T12_11725) 2788074..2788274 + 201 WP_269674006.1 hypothetical protein -
O2T12_RS11730 (O2T12_11730) 2788277..2789746 + 1470 WP_269674007.1 phage portal protein -
O2T12_RS11735 (O2T12_11735) 2789736..2790746 + 1011 WP_269674008.1 Clp protease ClpP -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(14-76)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11271.15 Da        Isoelectric Point: 10.6676

>T266881 WP_163373295.1 NZ_CP114886:c2785888-2785601 [Endozoicomonas sp. GU-1]
MTYELDFSALAWKEWQKLNSTVREQFKAKLRKRLENPKVSKDKLSGQKDCYKIKLRNSGYRLVYQVLDDVVVVFVISVGK
RERSEAYKAAQKRLR

Download         Length: 288 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9255.59 Da        Isoelectric Point: 4.3304

>AT266881 WP_163373296.1 NZ_CP114886:c2786132-2785878 [Endozoicomonas sp. GU-1]
MASVHPILADVSAGISELKKNPMAVLKEANGETVAILNRNQPVFYAVPAHVYEAMLDALDDLELAAIVEERKNDERIRVN
IDDL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References