Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 1565669..1566468 Replicon chromosome
Accession NZ_CP114886
Organism Endozoicomonas sp. GU-1 strain Ap1-3

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag O2T12_RS06705 Protein ID WP_269673118.1
Coordinates 1565956..1566468 (+) Length 171 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag O2T12_RS06700 Protein ID WP_269673117.1
Coordinates 1565669..1565938 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2T12_RS06680 (O2T12_06680) 1561263..1562570 + 1308 WP_269673112.1 tyrosine--tRNA ligase -
O2T12_RS06685 (O2T12_06685) 1562708..1563286 - 579 WP_269673113.1 AmmeMemoRadiSam system protein A -
O2T12_RS06690 (O2T12_06690) 1563448..1564227 - 780 WP_269673114.1 AmmeMemoRadiSam system protein B -
O2T12_RS06695 (O2T12_06695) 1564441..1565541 + 1101 WP_269676946.1 AmmeMemoRadiSam system radical SAM enzyme -
O2T12_RS06700 (O2T12_06700) 1565669..1565938 + 270 WP_269673117.1 DUF1778 domain-containing protein Antitoxin
O2T12_RS06705 (O2T12_06705) 1565956..1566468 + 513 WP_269673118.1 GNAT family N-acetyltransferase Toxin
O2T12_RS06710 (O2T12_06710) 1566503..1566934 + 432 WP_269676033.1 YkgJ family cysteine cluster protein -
O2T12_RS06715 (O2T12_06715) 1567021..1568040 - 1020 WP_269673119.1 alcohol dehydrogenase AdhP -
O2T12_RS06720 (O2T12_06720) 1568355..1569899 - 1545 WP_269673120.1 maltoporin LamB -
O2T12_RS06725 (O2T12_06725) 1570253..1570744 - 492 WP_269673121.1 DUF2244 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(90-146)

Antitoxin

Vibrio phage ICP1, Orf50

(5-80)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 19108.35 Da        Isoelectric Point: 7.9677

>T266878 WP_269673118.1 NZ_CP114886:1565956-1566468 [Endozoicomonas sp. GU-1]
VELDKGIHDRASFDCGETELNLFIQTQASKHMQAGISRTMVLPASNPFPNQKIPICAFYSITPGSICRDTLPEALVKKLP
RYPVPVFLIAQLAVHREFQGEGLGKICLVNALKYLWEINAHMRAYAIIVDCLTDAAEQFYAKYGFEVLCEHNGKVRMFLP
MKTVARLFSS

Download         Length: 513 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9998.47 Da        Isoelectric Point: 4.5958

>AT266878 WP_269673117.1 NZ_CP114886:1565669-1565938 [Endozoicomonas sp. GU-1]
MANARLDLRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATQVISEYEKMTVENDVFDRFTEACEKAKAPNKALLAAL
TFTEEKSVK

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References