Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 712655..713297 Replicon chromosome
Accession NZ_CP114871
Organism Caulobacter sp. NIBR2454

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag O5K31_RS03490 Protein ID WP_269715879.1
Coordinates 712995..713297 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag O5K31_RS03485 Protein ID WP_269715877.1
Coordinates 712655..712951 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O5K31_RS03445 707934..708347 + 414 WP_269715862.1 fosfomycin resistance glutathione transferase -
O5K31_RS03450 708464..709549 - 1086 WP_269715864.1 5-(carboxyamino)imidazole ribonucleotide synthase -
O5K31_RS03455 709555..710046 - 492 WP_269715865.1 5-(carboxyamino)imidazole ribonucleotide mutase -
O5K31_RS03460 710135..710350 - 216 WP_269715867.1 DUF465 domain-containing protein -
O5K31_RS03465 710415..710861 - 447 WP_269715869.1 TIGR02444 family protein -
O5K31_RS03470 710858..711460 - 603 WP_269715871.1 UbiX family flavin prenyltransferase -
O5K31_RS03475 711568..711741 + 174 WP_269715873.1 DUF465 domain-containing protein -
O5K31_RS03480 711800..712510 - 711 WP_269715875.1 DUF1013 domain-containing protein -
O5K31_RS03485 712655..712951 - 297 WP_269715877.1 putative addiction module antidote protein Antitoxin
O5K31_RS03490 712995..713297 - 303 WP_269715879.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O5K31_RS03495 713362..714327 - 966 WP_269716993.1 NAD(P)H-quinone oxidoreductase -
O5K31_RS03500 714413..714619 + 207 WP_269715881.1 DUF1192 domain-containing protein -
O5K31_RS03505 714708..715235 + 528 WP_269715883.1 DUF1465 family protein -
O5K31_RS03510 715426..715653 - 228 WP_269715885.1 50S ribosomal protein L31 -
O5K31_RS03515 715769..717622 + 1854 WP_269715887.1 ABC transporter transmembrane domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-95)

Antitoxin

Uncharacterized protein HI1420

(2-92)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11115.86 Da        Isoelectric Point: 10.6498

>T266874 WP_269715879.1 NZ_CP114871:c713297-712995 [Caulobacter sp. NIBR2454]
VVEVRQTAEFAAWFGGLRDLVARTRITARIDQLAYGLKGDVKAVGEGVRELRIHVGPGYRVYIKEHGGTLTILLCGGDKS
SQERDIRRAKEIARRVVKTP

Download         Length: 303 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10158.45 Da        Isoelectric Point: 4.9654

>AT266874 WP_269715877.1 NZ_CP114871:c712951-712655 [Caulobacter sp. NIBR2454]
MTATTPFNAADHIETPEQAAVFLDEALATGDAGYIQHALGVLARSKGMTHLADATGLGRQGLYKALAEDGSPKFETVLNV
VRALGIQLHATLADQAAA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References