Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1928613..1928758 Replicon chromosome
Accession NZ_CP114853
Organism Klebsiella pneumoniae strain S245

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1928649..1928751 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1928613..1928758 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O5O52_RS09345 1923743..1925803 + 2061 WP_004148850.1 oligopeptidase B -
O5O52_RS09350 1925807..1926466 - 660 WP_032435029.1 exodeoxyribonuclease X -
O5O52_RS09355 1926545..1926775 - 231 WP_002911406.1 DNA polymerase III subunit theta -
O5O52_RS09360 1926888..1927262 + 375 WP_004151448.1 CopC domain-containing protein YobA -
O5O52_RS09365 1927266..1928135 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
O5O52_RS09370 1928152..1928490 + 339 WP_002911404.1 YebY family protein -
- 1928613..1928758 - 146 - - Antitoxin
- 1928649..1928751 + 103 - - Toxin
O5O52_RS09375 1929126..1929269 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
O5O52_RS09380 1929374..1930342 - 969 WP_004151446.1 VirK/YbjX family protein -
O5O52_RS09385 1930499..1931152 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
O5O52_RS09390 1931149..1931340 - 192 WP_002911395.1 YebW family protein -
O5O52_RS09395 1931438..1931677 - 240 WP_002911393.1 YebV family protein -
O5O52_RS09400 1931793..1933226 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T266859 NZ_CP114853:1928649-1928751 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT266859 NZ_CP114853:c1928758-1928613 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References