Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 4306778..4307297 Replicon chromosome
Accession NZ_CP114801
Organism Citrobacter sp. 21OH12SH02A-Citro

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag O6D90_RS20770 Protein ID WP_016155559.1
Coordinates 4306778..4307059 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0V9JX71
Locus tag O6D90_RS20775 Protein ID WP_016155558.1
Coordinates 4307049..4307297 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O6D90_RS20755 (4303782) 4303782..4304246 + 465 WP_016155562.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
O6D90_RS20760 (4304265) 4304265..4304786 - 522 WP_016155561.1 hypothetical protein -
O6D90_RS20765 (4304786) 4304786..4306750 - 1965 WP_016155560.1 type VI secretion system tip protein TssI/VgrG -
O6D90_RS20770 (4306778) 4306778..4307059 - 282 WP_016155559.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O6D90_RS20775 (4307049) 4307049..4307297 - 249 WP_016155558.1 hypothetical protein Antitoxin
O6D90_RS20780 (4307395) 4307395..4307523 - 129 WP_016155557.1 hypothetical protein -
O6D90_RS20785 (4307592) 4307592..4308065 - 474 WP_016155556.1 hypothetical protein -
O6D90_RS20790 (4308108) 4308108..4310609 - 2502 WP_016155555.1 type VI secretion system ATPase TssH -
O6D90_RS20795 (4310600) 4310600..4311547 - 948 WP_016155554.1 type VI secretion system baseplate subunit TssG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11004.76 Da        Isoelectric Point: 10.4466

>T266852 WP_016155559.1 NZ_CP114801:c4307059-4306778 [Citrobacter sp. 21OH12SH02A-Citro]
MTYNLEFLDVALKEWRKLSPTLREQFKKKLAERLENPHVPAARLSGKLHRYKIKLRSAGYRLVYQVEDEQVVVLVIAVGR
RDGDEVYHQANRR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8987.28 Da        Isoelectric Point: 4.7513

>AT266852 WP_016155558.1 NZ_CP114801:c4307297-4307049 [Citrobacter sp. 21OH12SH02A-Citro]
MPFHILTKTAASITDLKRNPMGTVNAGEGEAVAILNRNEPAFYCVPPAVYAYLLELAEDAELNRIADEREGGKRIKVSLN
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0V9JX71

References