Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 4417096..4417913 Replicon chromosome
Accession NZ_CP114791
Organism Sphingomonas sp. NIBR02145

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag O3305_RS20305 Protein ID WP_269574157.1
Coordinates 4417371..4417913 (+) Length 181 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag O3305_RS20300 Protein ID WP_269574156.1
Coordinates 4417096..4417380 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3305_RS20260 (O3305_20260) 4412147..4412611 - 465 WP_269574148.1 DoxX family protein -
O3305_RS20265 (O3305_20265) 4412672..4412950 - 279 WP_269574149.1 DUF2282 domain-containing protein -
O3305_RS20270 (O3305_20270) 4413162..4413701 + 540 WP_269574150.1 sigma-70 family RNA polymerase sigma factor -
O3305_RS20275 (O3305_20275) 4413698..4414339 + 642 WP_269574151.1 DUF1109 domain-containing protein -
O3305_RS20280 (O3305_20280) 4414423..4414695 + 273 WP_269574152.1 hypothetical protein -
O3305_RS20285 (O3305_20285) 4414760..4415590 + 831 WP_269574153.1 DUF692 domain-containing protein -
O3305_RS20290 (O3305_20290) 4415587..4416378 + 792 WP_269574154.1 DNA-binding domain-containing protein -
O3305_RS20295 (O3305_20295) 4416589..4416786 + 198 WP_269574155.1 hypothetical protein -
O3305_RS20300 (O3305_20300) 4417096..4417380 + 285 WP_269574156.1 DUF1778 domain-containing protein Antitoxin
O3305_RS20305 (O3305_20305) 4417371..4417913 + 543 WP_269574157.1 GNAT family N-acetyltransferase Toxin
O3305_RS20310 (O3305_20310) 4418585..4419025 - 441 WP_269574158.1 hypothetical protein -
O3305_RS20315 (O3305_20315) 4419052..4421424 - 2373 WP_269574159.1 TonB-dependent receptor -
O3305_RS20320 (O3305_20320) 4421429..4422418 - 990 WP_269574160.1 FecR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 4260006..4418757 158751


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(54-157)

Antitoxin

Vibrio phage ICP1, Orf50

(4-94)


Sequences

Toxin        


Download         Length: 181 a.a.        Molecular weight: 19474.39 Da        Isoelectric Point: 8.8224

>T266838 WP_269574157.1 NZ_CP114791:4417371-4417913 [Sphingomonas sp. NIBR02145]
MGVIEPLGAPRPAYAAPTPITADHRLDGFECGKPPLDSWLKTHALDNEGKASRTYVVDARLGEDAGNVVAYYTLAFGSVT
REEVPKKIRQGLPNPVPVMVLGRLAVDKRHAGKGLGPALLREALQRTAEASRIGGLRALIVHAIDDDAVSFYTKYGFQIF
PAGSRTLFLPIETVRQSIVE

Download         Length: 543 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10413.87 Da        Isoelectric Point: 4.8362

>AT266838 WP_269574156.1 NZ_CP114791:4417096-4417380 [Sphingomonas sp. NIBR02145]
MASVAERPKADTSITMRLPVQTRDLIDRAAATIDKSRTEFVLESARQRAIDVLLDQRVFHLDAEASDALADVLENPPAPV
DALRKLMASKSPWE

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References