Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 73352..73890 Replicon plasmid unnamed4
Accession NZ_CP114790
Organism Roseibium sp. Sym1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag O6760_RS33290 Protein ID WP_075282926.1
Coordinates 73352..73645 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag O6760_RS33295 Protein ID WP_075282925.1
Coordinates 73642..73890 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O6760_RS33275 70923..71174 + 252 WP_168693775.1 TraC family protein -
O6760_RS33280 71203..71409 + 207 Protein_69 conjugal transfer protein TraD -
O6760_RS33285 71399..73318 + 1920 WP_269586478.1 Ti-type conjugative transfer system protein TraG -
O6760_RS33290 73352..73645 - 294 WP_075282926.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O6760_RS33295 73642..73890 - 249 WP_075282925.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
O6760_RS33300 74136..74300 - 165 WP_168693765.1 hypothetical protein -
O6760_RS33305 74664..74924 + 261 WP_269586477.1 WGR domain-containing protein -
O6760_RS33310 75012..75329 - 318 WP_075282947.1 DUF736 domain-containing protein -
O6760_RS33315 76053..76982 - 930 WP_269586476.1 zincin-like metallopeptidase domain-containing protein -
O6760_RS33320 77253..77438 - 186 WP_269586475.1 hypothetical protein -
O6760_RS33325 77770..78165 - 396 WP_209171702.1 type II toxin-antitoxin system PemK/MazF family toxin -
O6760_RS33330 78158..78424 - 267 WP_209171699.1 type II toxin-antitoxin system prevent-host-death family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..89413 89413


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11307.91 Da        Isoelectric Point: 6.9776

>T266836 WP_075282926.1 NZ_CP114790:c73645-73352 [Roseibium sp. Sym1]
MKVLVFSPAAKMDLEHIWDHSVEIWGLDQADRYLDEIRDACFGLASGDRRGRPVDVRAGYLKYATGVHMVYFRDHVDRLE
VIRILHQRQDVSRNLPT

Download         Length: 294 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9159.14 Da        Isoelectric Point: 5.7065

>AT266836 WP_075282925.1 NZ_CP114790:c73890-73642 [Roseibium sp. Sym1]
MARNTSVTLGDHFTGFISDQVQTGRYGSASDVVRAGLRLLEEHEAKVKALQDALIAGERSGEPQPFDFDEFKARKRAEYE
SR

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References